Results 41 to 50 of about 78,481 (217)

MANAGEMENT PROCESSES RECONSTRUCTION OF HISTORICAL BUILDINGS SUPPORTED BY SMART TECHNOLOGY – A CASE STUDY OF FUZHOU CITY [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
This research is based on the projects that Fuzhou has carried out and in developing, regarding to historical building survey, registration, documentation, publication, construction, and daily management business.
W. Qu, M. J. Li, X. Q. Zhang, Z. Wang
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Greengrass, Mark and Lorna Hughes, eds., 2008. The Virtual Representation of the Past. Farnham: Ashgate. 226 pages.

open access: yesDigital Medievalist, 2011
This volume focuses on the possibilities offered by modern computer systems with respect to historical research. The papers included not only deal with contemporary projects, but also offer a wider, more theoretical view on the potentialities of computer-
Renaud Beeckmans
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Enhancing data reuse in tunnelling site investigation through transfer learning-based historical data mining

open access: yesUnderground Space
Vast amounts of valuable historical tunnelling site investigation data remain underutilized due to inefficient content-based archiving and searching tools. This study introduces a novel data-driven framework that integrates transfer learning with reverse
Jiawei Xie   +5 more
doaj   +1 more source

Archival analysis of the construction projects of the barracks during the Franco dictatorship: the example of Badajoz province (1943-1971)

open access: yesBrocar. Cuadernos de investigación histórica, 2020
This paper deals with the study of the documentation of construction projects of Guard Barracks Houses that took place in Extremadura after the Civil War Española (1936-1939).
Isabel Mª Sanz Caballero   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

An Examination of Concord Errors in the Academic Writings of Students at a Technical University in Ghana [PDF]

open access: yesJournal of Education and Learning Technology
This study explored the teachers’ challenges in using local history projects to develop learners’ historical skills. Despite the importance of local history projects in developing learners’ historical skills and knowledge, there is evidence that teachers
Gifty Serwah Mensah   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

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