Results 51 to 60 of about 78,481 (217)

Narrativas de histórias: um estudo preliminar na gestão de projetos de Tecnologia da Informação

Ciência da Informação, 2008
Narrativas de histórias é uma técnica de gestão do conhecimento para compartilhamento de experiências, pensamentos e valores no ambiente organizacional.
Valério Brusamolin, Eduardo Amadeu Dutra Moresi   +1 more
doaj  

Problems of assessing the duration and cost of restoration projects on the example of Poland, Slovakia and Lithuania

Przegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2018
The restoration of existing structures, especially historical ones, is a complicated endeavour. The often insuffi cient identification of the extant state of a building, the possibility of archaeological fi ndings and the necessary procedures involving ...
Elżbieta Radziszewska-Zielina, Bartłomiej Szewczyk, Bartłomiej Sroka, Grzegorz Śladowski, Peter Mesároš, Vladislavas Kutut   +5 more
doaj   +1 more source

Teachers’ Challenges of Using Local History Projects to Develop Learners’ Historical Skills – A Case Study of Motheo Education District [PDF]

Journal of Education and Learning Technology
This study explored the teachers’ challenges in using local history projects to develop learners’ historical skills. Despite the importance of local history projects in developing learners’ historical skills and knowledge, there is evidence that teachers
Zwelinjane Mbatha, Boitumelo Moreeng
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

QR-CODES AND TOURISM. THE EXPERIENCE OF CREATING DIGITAL CONTENT ABOUT HISTORICAL AND CULTURAL SITES IN THE CONTEXT OF TOURISM PORTALS DEVELOPMENT

Вестник Кемеровского государственного университета, 2015
The paper is devoted to the analysis of the process of creation and functioning of the Russian tourist portals linked with the use of technologies of augmented reality (qr-codes).
E. A. Kirsanova
doaj  

The city branding potential of Sakarya: A tourism-oriented evaluation

Journal of Design for Resilience in Architecture and Planning
With the rise of global competition, developing city branding strategies has become vital for urban centres. The unique features and values of cities, especially their geographical, cultural, and historical traits, play a crucial role in shaping city ...
Esra Parıldı, Güliz Öztürk
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

History as an Instrument in the Development of Historical Danish Villages

Buildings, 2016
A central contemporary societal discussion in Denmark concerns settlements that have poor connectivity and are geographically distant to main towns and cities. These settlements are called “outskirts.” Historically significant villages in these outskirts
Morten Birk Jørgensen
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source