Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Works of the Russian historians of the first half of the XIX century had a number of signs of similarity to works of fiction. In particular, one of such signs was that the plot reminded a literary work plot.
O. N. Shevtsova
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Promoting positive attitudes towards science and religion among sixth-form pupils : dealing with scientism and creationism [PDF]
A sample of 187 female students, attending a sixth-form study day on religious studies, completed a questionnaire containing four scales concerned with assessing: attitude toward theistic religion, attitude toward science, scientism and creationism.
Leslie J. Francis +3 more
core +1 more source
THE RUSSIAN-GERMAN HISTORIANS COMMISSION: FROM POLITICAL DIALOGUE TO FRUITFUL SCIENTIFIC COOPERATION
The article discusses the creation and activity of the Joint Commission for the Study of the Recent History of Russian-German Relations.
M. V. Raschesova
doaj
STAVROPOL TERRITORY IN RUSSIAN HISTORICAL SCIENCE OF THE 20-30s OF THE XX CENTURY
The article shows what problems interested humanities scholars and publicists in the prewar period of the Soviet history and how these problems were covered from new methodological positions. The works created at that time by historians of the old school
T. Nevskaya
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Exploring the tension and synergies between science and technology in science education
This chapter explores the way in which technology has been introduced through and by science educators in Australasia in the last 25 years. A number of themes have arisen in this time from using technology to engage students in science, exploring the ...
Jones, Alister
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Naval Postgraduate School Historical Highlights: 1963: When Science was Science! [PDF]
Historical Highlights are provided by the Dudley Knox ...
Berry, Irene
core

