Results 91 to 100 of about 426,189 (312)

The Mineralogy Manuscript Preserved in the Archivo General de Palacio, (Madrid, Spain): A Case Study

open access: yesGeosciences
The manuscript of the Mineralogical lessons for the 1824–1825 course being held at the Royal Cabinet of Natural History had been found in the Archivo General de Palacio (AGP; Madrid, Spain) by the priest Donato García, who replaced Christian Herrgen and ...
María Rosario Alcalde-Fuentes   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Historical and philosophical perspectives of science. Preliminaries

open access: yes, 1970
1 online resource (PDF, peliminaries, including title page, foreword, preface, synopsis, and table of contents). (1970). Historical and philosophical perspectives of science. Preliminaries.

core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Scholar and teacher: V.A. Kitaev at the history department of Volgograd State University

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2013
Vladimir A. Kitaev was born 1941. He was the first dean of the Faculty of History and the first head of the Department of History of the USSR (now the Department of History of Russia) of Volgograd State University, reputable scientist, recognized expert ...
Kuznetsov Oleg Viktorovich
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Innovation in science and organizational renewal: historical and sociological perspectives

open access: yes, 2016
This book looks at the types of new research organizations that drive scientific innovation and how ground-breaking science transforms research fields and their organization.
Heinze, Thomas, Münch, Richard
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modern Comprehension of the Treaty of Lausanne (1923): Historical Documentary, Searching for Rodakis by Kerem Soyyilmaz

open access: yesHistories
This study analyzes the award-winning documentary film Searching for Rodakis, directed by Kerem Soyyilmaz, produced in 2023. The aim of this study is the historic comprehension and analysis of this filmic narrative in the field of social–semiotic ...
Theodora Semertzian   +3 more
doaj   +1 more source

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