Results 121 to 130 of about 2,470,978 (359)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Orbital parameters of V 0332+53 from 2015 giant outburst data

open access: yes, 2015
We present the updated orbital solution for the transient Be X-ray binary V 0332+53 comple- menting historical measurements with the data from the gamma-ray burst monitor onboard Fermi obtained during the outburst in June-October 2015.
Doroshenko, V.   +2 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Historical Y. pestis Genomes Reveal the European Black Death as the Source of Ancient and Modern Plague Pandemics [PDF]

open access: bronze, 2016
Maria A. Spyrou   +14 more
openalex   +1 more source

SOURCES OF INTERNATIONAL LAW: HISTORICAL AND THEORETICAL ANALYSIS

open access: diamond, 2022
О. К. Канєнберг-Сандул
openalex   +1 more source

Authenticating Turkey Red Textiles through Material Investigations by FTIR and UHPLC [PDF]

open access: yes, 2017
Nineteenth-century Turkey red, a cotton textile dyed by a peculiar and unique process, is found in many collections around the world. It was known for its bright colour and remarkable fastness to light exposure and washing.
France, David   +4 more
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

343 HISTORY AND SOURCE STUDIES: ARE DIPLOMATIC DOCUMENTS HISTORICAL SOURCES?

open access: yesAstra Salvensis, 2019
Historical science assumes that the basic research activity of a historian is work with historical sources. The role and meaning of historical sources in historical researches is gradually replaced the knowledge of the previous historiography.
Gulziya Akmadiyeva   +4 more
doaj  

Source control SUDS delivery on a global scale and in Scotland including approach by responsible organisations and professional groups [PDF]

open access: yes, 2013
Background to researchThe Sustainable Urban Drainage Scottish Working Party via CREW commissioned this work on the implementation of source control for SUDS in Scotland.
Berwick, Neil   +4 more
core  

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