Results 111 to 120 of about 12,078,524 (337)
The Constitution of Social Practices [PDF]
, 2017 Practices – specific, recurrent types of human action and activity – are perhaps the most fundamental "building blocks" of social reality. This book argues that the detailed empirical study of practices is essential to effective social-scientific ...
McMillan, Kevin
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
I confini di Urania. La geografia come limes perdurante [PDF]
Diacronie. Studi di Storia Contemporanea, 2009 The notion of “inner boundary” is the key point in understanding the internal dynamics of independence and autonomy movements that have made their appearance in Corsica and Sicily during the nineteenth and twentieth centuries.
Deborah Paci
doaj
Noël Carroll : eine Bibliographie [PDF]
, 2010 Das Werk des Philosophen und Filmtheoretikers Noël Carroll ist außerordentlich vielgestaltig, über mehrere Disziplinen verstreut, umfaßt allgemeine Arbeiten zur ästhetischen Theorie (auf diesem Gebiet ist Carroll vor allem in den letzten Jahren aktiv ...
Wulff, Hans Jürgen
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
HeliyonIntroduction: No markers have been used to diagnose historical peritoneal dialysis (PD)-related peritonitis. Cyclophilin A (CypA) is associated with glucose toxicity and inflammation.
Shang-Feng Tsai +3 more
doaj +1 more source
ACTUALIZATION OF THE ZONE OF PROXIMAL DEVELOPMENT OF JUNIOR SCHOOLCHILDREN WITH MENTAL RETARDATION BY MEANS OF A LITERARY GAME [PDF]
Krymskij Naučnyj Vestnik, 2017 The article discusses the concept of "zone of proximal development" from the standpoint of the cultural-historical approach, raises the problem of specificity of this concept in the modern system of education, justifies the use of literary games as an ...
M.E. Starostina, D.A. Starostin
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source