Results 101 to 110 of about 87,097 (305)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

I confini di Urania. La geografia come limes perdurante [PDF]

Diacronie. Studi di Storia Contemporanea, 2009
The notion of “inner boundary” is the key point in understanding the internal dynamics of independence and autonomy movements that have made ​​their appearance in Corsica and Sicily during the nineteenth and twentieth centuries.
Deborah Paci
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genre specificity and methodology for the creation of artistic and historical works (based on the historical Tatar novel)

, 2020
In this paper the Tatar historical novel - dialogue of Nurihan Fattah "Whistling Arrows" specifically and objectively identified the methodology for the artistic and historical works creation, which is a strict adherence to the historical chronicle in ...
Zakirova V., Khairutdinova R.
core  

Dialysate cyclophilin A as a predictive marker for historical peritonitis in patients undergoing peritoneal dialysis

Heliyon
Introduction: No markers have been used to diagnose historical peritoneal dialysis (PD)-related peritonitis. Cyclophilin A (CypA) is associated with glucose toxicity and inflammation.
Shang-Feng Tsai, Cheng-Hsu Chen, Ming-Ju Wu, Mingli Hsieh   +3 more
doaj   +1 more source

ACTUALIZATION OF THE ZONE OF PROXIMAL DEVELOPMENT OF JUNIOR SCHOOLCHILDREN WITH MENTAL RETARDATION BY MEANS OF A LITERARY GAME [PDF]

Krymskij Naučnyj Vestnik, 2017
The article discusses the concept of "zone of proximal development" from the standpoint of the cultural-historical approach, raises the problem of specificity of this concept in the modern system of education, justifies the use of literary games as an ...
M.E. Starostina, D.A. Starostin
doaj  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Generality, Specificity And Discovery

This paper offers a meta-theory concerning the relation between the general and the specific in science. This issue was recently called back to attention by Hodgson (2001). A heuristic of discovery, developed in earlier work (Nooteboom 1992, 1996, 1999b,
Nooteboom, B.
core  

Critical Theory and Antisemitism: Interrogating the Historical Specificity of the Enlightenment [PDF]

, 2015
Me propongo revisitar los "Elementos de antisemitismo" en Dialéctica del Iluminismo a la luz del desarrollo posterior de la teoría crítica. Como se sigue de las críticas de Habermas o Wellmer, el texto citado encierra el peligro de caer en una filosofía ...
Martín, Facundo, Martín, Facundo Nahuel   +1 more
core  

Integrating phylogenetic and ecological distances reveals new insights into parasite host specificity

, 2017
The range of hosts a pathogen infects (host specificity) is a key element of disease risk that may be influenced by both shared phylogenetic history and shared ecological attributes of prospective hosts. Phylospecificity indices quantify host specificity
Clegg, Sonya, Nicholas J. Clark, Clark, NJ, Clark, Nicholas J., Clark, Nick, Clegg, SM, Clegg, Sonya M., Sonya M. Clegg   +7 more
core   +1 more source