Results 151 to 160 of about 560,734 (316)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Bob Hope and Dixie Lee Etheridge PSA order form

open access: yes, 1976
Order form for a public service announcement given by Bob Hope and Dixie Lee Etheridge, Miss Wheelchair 1976. The form is printed on Bob Hope National Honorary Chairman letterhead, with the Miss Wheelchair America logo printed in the top left ...
Miss Wheelchair America Pageant.
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Scouting, April 8, 1920: Containing the Tenth Annual Report of the Boy Scouts of America

open access: yes, 1920
Bi-weekly publication of the Boy Scouts of America, written for Boy Scout leaders, officials, and others interested in the work of the Scouts. It includes articles about events and activities, updates from the national headquarters, topical columns and ...
Boy Scouts of America
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Biological Control in Latin America and the Caribbean: Its Rich History and Bright Future

open access: yes, 2020
The book summarizes the history of biological control in Latin America and the Caribbean. Few publications provide historical detail and the records are, therefore, fragmented until now.
Van Lenteren, Joop C.   +3 more
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Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Vicki Cockril boards the Miss Wheelchair America van

open access: yes, 1979
Vicki Cockril, Miss Wheelchair Tennessee, smiles as she pushes her wheelchair into the MWA ...
Miss Wheelchair America Pageant.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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