Results 171 to 180 of about 10,380,327 (309)

Pediatric lynch-associated melanoma arising in ovarian teratoma: a case report. [PDF]

Gynecol Oncol Rep
Alcheikh R, Boyd JO, Saab S, Albuquerque P, Egler R, Lynam SK.   +5 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Brought with the wind: A case of melioidosis acquired in the United States presenting with multiple pulmonary nodules. [PDF]

PLoS Negl Trop Dis
Garcia-Santisteban R, Kaufman M, Jacqueline Chung HT, Khella R, Pousa A, Kujundzic W, Mbaga I, Voin V.   +7 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Shaped by mountains, driven by climate: the rise of the Neotropical Carex sect. Fecundae. [PDF]

Ann Bot
Lois R, García Moro P, Morales Alonso A, Cano A, Dorr LJ, Escudero M, González-Elizondo MS, Reznicek AA, Ruiz-Sánchez E, Wen J, Acedo C, Jiménez Mejías P.   +11 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Prevalence and characteristics of sex trafficking among youth experiencing homelessness: A cross-sectional study. [PDF]

PLoS One
Fernández-Sánchez H, Jones J, Arandhara U, Padhye N, Nyamathi A, Lightfoot M, Quadri Y, Paul M, Businelle MS, Maria DS.   +9 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

A community health worker pilot intervention to increase patient portal use among people with HIV. [PDF]

PLOS Digit Health
Whitney E, Devlin SA, Friedman EE, Mason JA, Patil Vilas S, Kagarmanova A, Clark N, Laiteerapong N, Pagkas-Bather J, Brewer RA, Schneider J, Grant JE, Pollack H, Bischoff D, Ridgway JP.   +14 more
europepmc   +1 more source