Results 161 to 170 of about 560,734 (316)

The evolutionary history and unique genetic diversity of Indigenous Americans. [PDF]

Nature
Castro E Silva MA, Nunes K, Ribeiro MR, Passarelli-Araujo H, Lemes RB, Kimura L, Sacuena P, G Amorim CE, Bortolini MC, Mill JG, Guerreiro JF, Barbieri C, Hernández-Zaragoza DI, Walter A, Chowdhury TN, Macías-Herrera D, Lara-Riegos JC, Del Castillo-Chávez O, Zurita C, Tito-Álvarez AM, Vásquez-Domínguez E, Moo-Mezeta ME, Torres-Romero JC, Aguilar-Campos A, Serrano-Osuna R, Parolín ML, Bravi CM, Ramallo V, Bailliet G, Revollo S, Sandoval JR, Fujita R, Barquera R, Santos FR, Comas D, Hünemeier T.   +35 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Validation of Risk Models for Predicting Post-SVR HCC in Real-World Surveillance Across Global Geographic Regions. [PDF]

Liver Int
Toyoda H, Hoshida Y, Parikh ND, Jalal PK, Piñero F, Mendizabal M, Ridruejo E, Cheinquer H, Casadei-Gardini A, Kanneganti M, Weinmann A, Peck-Radosavljevic M, Dufour JF, Radu P, Shiha G, Soliman R, Sarin SK, Kumar M, Wang JH, Tangkijvanich P, Sukeepaisarnjaroen W, Atsukawa M, Uojima H, Nozaki A, Nakamuta M, Takaguchi K, Hiraoka A, Abe H, Matsuura K, Watanabe T, Shimada N, Tsuji K, Ishikawa T, Mikami S, Itobayashi E, Johnson PJ, Singal AG.   +36 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Air America pilot's cap and badge

, 2008
Air America pilot's cap and ...

core  

Letter regarding unravelling the genomic landscape of Canadian <i>Borrelia burgdorferi</i>: a comparison across global strains; Piot <i>et al</i>. Microbial Genomics 2026;12:001606. [PDF]

Microb Genom
Ogden NH, Mechai S, Margos G, Feil EJ.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

History of the Michigan Conference, Wesleyan Methodist Church of America,

, 1940
"History of the Woman's home and foreign missionary society, Michigan conference, Wesleyan Methodist church of America, 1890-1940 [by] Mrs. Mabel Perrine": 121 p. at end.Issued with Mrs.
Rennells, Charles S. (Charles Stephen), 1873-1962., Perrine, Mabel, Mrs. History of the Woman's home and foreign missionary society, Michigan conference, Wesleyan Methodist Church of America.   +1 more
core  

Longitudinal brain health and neurological correlates of sexual strangulation in young adults: Study protocol for a prospective cohort study. [PDF]

PLoS One
Kawata K, Buddenbaum CV, Huibregtse ME, Sweeney SH, Cheng H, Rosenberg M, Finn D, Newman SD, Wetzel GM, Hohne JM, West KM, McGuire M, Miller KH, Ellis G, Galper EF, Feiner JR, Valera E, Herbenick D.   +17 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source