Results 161 to 170 of about 10,380,327 (309)

Native America. A History.

Historia Social y de la Educación, 2019
Vladia Ionescu
doaj   +1 more source

New Country for Old Mice: The Recent Colonization History of Mus musculus domesticus in the Americas. [PDF]

Genome Biol Evol
Agwamba KD, Gabriel SI, Searle JB, Wall J, Nachman MW.   +4 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The Emergence of Modern America 1865-Present

, 2018
This subject studies the changing structure of American politics, economics, and society from the end of the Civil War to the present. We will consider secondary historical accounts and primary documents to examine some of the key issues in the ...
Faculty, History Department
core  

Ancient Ecuadorian genomes reveal millennia of genetic continuity on the Pacific Coast of South America. [PDF]

PNAS Nexus
Lindo J, Rivas Alava D, Juengst S, Pryor Y, Joseph SK, Ortiz Aguilu JJ, Lunniss R.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Official Documents of the Lutheran Church in America, 1960

, 2014
This booklet of Official Documents of the Lutheran Church in America includes: Constitution of the Lutheran Church in America. By-Laws of the Lutheran Church in America. Approved Constitution for Synods of the Lutheran Church in America.
Lutheran Church in America;
core  

Cervical spinal cord compression in children and adolescents with 22q11.2 deletion syndrome. [PDF]

Brain Spine
Boxem JA, Houben ML, Ecker ML, Schwartz ES, Schlösser TP, Zackai E, Crowley TB, Mink van der Molen AB, McDonald-McGinn DM, Tucker AM.   +9 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source