Results 181 to 190 of about 2,923,127 (308)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Genomic structure, ecological suitability and biogeographic history of the palm <i>Acrocomia aculeata</i> across Central America. [PDF]

Front Plant Sci
Morales-Marroquín JA, López de Paz ER, Silva-Rivera R, Francisconi AF, Orellana-Hernandez RA, Palacios JM, Araya-Valverde E, Arnáez Serrano E, Rabelo-Araujo JVDS, Garcia CB, Scaketti M, Colombo CA, Díaz-Hernández BG, Pinheiro JB, Zucchi MI.   +14 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Evidence for Historic and Ongoing Human-Mediated Dispersal of Yeast. [PDF]

Mol Ecol
Ruffieux M, Smukowski Heil C.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Latin America: History and Criticism

Iberoamericana. América Latina - España - Portugal, 2016
Albert Manke, Stefan Rinke, Josef Opatrný, Raquel Gil Montero, Luz Ailin Lozada, Raquel Arias Careaga, Peter Fleer, Ludger Pries, Katrina Böse, Veit Straßner   +9 more
doaj   +1 more source

Correction for Liao et al., Noncanonical genetic markers resolve the pre-GOE emergence of aerobic bacteria in Earth's history. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Challenging Case: Health Care Professionals as Cultural Brokers for a Boy From Central America With Attention-Deficit Hyperactivity Disorder and Trauma and Stressor-related Disorder. [PDF]

J Dev Behav Pediatr
Cerda N, Shahidullah JD, Kates C, Marquez A, Diekroger EA, Fogler J.   +5 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Beyond the Colon: <i>Clostridioides</i> <i>d</i> <i>ifficile</i> Enteritis Presenting Following a Nissen Fundoplication. [PDF]

ACG Case Rep J
Alvina F, Nasr D, Singh K.
europepmc   +1 more source