Results 191 to 200 of about 9,940,766 (374)

Dual S-methoprene and Lysinibacillus sphaericus larvicide use leads to multiple independent, and not cross-resistance in Culex pipiens. [PDF]

PLoS One
Lopez K, Irwin P, Tomek M, Holub R, Paskewitz S, Bartholomay L, Clifton M.   +6 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Furuncular cutaneous myiasis after travel in South America: case report and epidemiologic, diagnostic and management considerations. [PDF]

Trop Dis Travel Med Vaccines
Blănaru AM, Toderan AR, Oancea A, Hristea A.   +3 more
europepmc   +1 more source

The Shock- Absorber Role of the Internal Public Debt in Colombia, 1923-2003. [PDF]

The hypothesis that the internal public debt has played the role of shock absorber in Colombia since 1923 is modelled. 1923 was an important landmark in the history of fiscal and monetary reforms in Colombia during the twentieth century.
Mauricio Avella Gómez
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Global sampling decline erodes science potential of natural history collections. [PDF]

Nat Commun
Forbes O, Young AG, Thrall PH.
europepmc   +1 more source

[Book review] "David S. Landes, The Wealth and Poverty of Nations: Why Some Are So Rich and Some So Poor" [PDF]

Europe, Japan, China, Asia, South America, Economic history ...
Nogami, Hiroki
core  

A comprehensive genomic history of extinct and living elephants

Proceedings of the National Academy of Sciences of the United States of America, 2018
E. Palkopoulou, E. Palkopoulou, Mark Lipson, Swapan Mallick, Swapan Mallick, Svend V. Nielsen, N. Rohland, Sina Baleka, Emil Karpinski, A. Ivancevic, Thu-Hien To, R. Kortschak, J. Raison, Z. Qu, Tat-Jun Chin, K. Alt, K. Alt, S. Claesson, L. Dalén, R. Macphee, H. Meller, A. Roca, O. Ryder, David I Heiman, Sarah K. Young, M. Breen, C. Williams, Bronwen L. Aken, Magali Ruffier, E. Karlsson, E. Karlsson, Jeremy Johnson, F. Palma, Jessica Alföldi, D. Adelson, T. Mailund, Kasper Munch, K. Lindblad-Toh, K. Lindblad-Toh, M. Hofreiter, H. Poinar, D. Reich, D. Reich, D. Reich   +43 more
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Columbia suicide severity rating scale screen scores in adults with Chiari malformation Type 1. [PDF]

PLoS One
Labuda R, Nolan E, Rabinowitz EP, Delahanty DL, Klinge PM, Allen PA.   +5 more
europepmc   +1 more source