Results 101 to 110 of about 17,748,027 (382)

THE RELEVANCE OF HISTORY IN THE GENERAL STUDIES PROGRAM OF UNIVERSITY OF SCIENCE AND TECHNOLOGY

Paramita: Historical Studies Journal, 2018
This paper examines the relevance of the discipline of the history to the study of science and Technology in Nigeria. It interrogates how historical memories have shaped the discipline of science with respect to innovation, creativity and technological ...
Oladiti Abiodun Akeem
doaj   +1 more source

General decay for a Timoshenko-type system for thermoelasticity of type III with delay, past history and distributed delay

, 2022
Salim Hamida, Salah Zitouni, Djamel Ouchenane   +2 more
openalex   +1 more source

The History of Macroeconomics from Keynes’s General Theory to the Present [PDF]

This paper is a contribution to the forthcoming Edward Elgar Handbook of the History of Economic Analysis volume edited by Gilbert Faccarello and Heinz Kurz.
Michel DE VROEY, Pierre MALGRANGE
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The use of digital technologies in the educational process of basic general, secondary general and secondary vocational education on the example of the study of regional studies (history of the Samara Region)

, 2023
Arina A. Sukhorukova, Sergey Olegovich Buranok   +1 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Towards a revision of the Palaearctic species of Aphodius Hellwig, 1798, subgenus Liothorax Motschulsky, 1860 (Coleoptera, Scarabaeidae, Aphodiinae) [PDF]

ZooKeys
The Palaearctic species of Aphodius Hellwig, 1798, subgenus Liothorax Motschulsky, 1860 are revised using a combination of chromosome analysis, molecular phylogenetics and morphological statistical analysis.
Robert B. Angus, Jason F. Maté, Elizabeth M. Angus, David Král   +3 more
doaj   +3 more sources

The Place of Science in General History [PDF]

, 1936
F. S. M.
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A Monument to Culture and Achievement: The Samurai Suit of Armor and Katana at Gettysburg College [PDF]

, 2018
Of the many artifacts found in Gettysburg College’s Musselman library, perhaps the most unusual and seemingly out of place may be the centuries-old replica of a samurai suit and katana standing guard over visitors and students from an oversized glass ...
Hauk, Carolyn
core   +1 more source