Results 31 to 40 of about 484,323 (266)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Pamiętnik Teatralny, 2018 In his work, Wirus mobilizacji, Wojciech Klimczyk presents a history of Western Europe interpreted through the changing dancing practices, or to use Klimczyk’s own vocabulary, an owerview of subsequent social choreographies.
Grzegorz Kondrasiuk
doaj +1 more source
"Battles for history" in the Russian-Ukrainian war from February 24, 2022 to the present [PDF]
Ante Portas, 2023 The proposed study focuses on the principled intellectual contests - "battles for history" - from the beginning of the Russian invasion of Ukraine on February 24, 2022 to the present day.
Roman Ofitsynsky, Yuriy Ofitsynsky
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Sociological aspects in the history of public health
RUDN journal of SociologyThe article is a brief review-recommendation of a non-sociological book that will be useful to any researcher in the field of sociology of medicine - for broadening general horizons by reading related and interdisciplinary sources and for developing ...
L. V. Pashigorova
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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EARLY MEDIEVAL HISTORY OF EASTERN EUROPE AT THE RECEPTION OF VICTOR PETROV (V. DOMONTOVYCH)
Київські історичні студії, 2019 The purpose of the study is to find out point of the view of the famous archaeologist, historian, scientist V. Petrov on to the socio-economic, political, ethnic development of early medieval Eastern Europe.
Vitaliy Andryeyev
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
BMC Health Services Research, 2009 Background Coronary heart disease (CHD) is the leading cause of death in the developed world, and its prevention a core activity in current UK general practice.
Kai Joe +8 more
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source