Results 51 to 60 of about 2,109,866 (309)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Sociological aspects in the history of public health

open access: yesRUDN journal of Sociology
The article is a brief review-recommendation of a non-sociological book that will be useful to any researcher in the field of sociology of medicine - for broadening general horizons by reading related and interdisciplinary sources and for developing ...
L. V. Pashigorova
doaj   +1 more source

Pimensions of poetics and genealogy of alternative history (ah) as a phenomenon of the literary process

open access: yesАктуальні питання суспільних наук та історії медицини, 2021
Measurements poetics and genealogy of alternative history (AI) as a phenomenon literary process. The main ones are considered in the article characteristics of subgenres of alternative history, their style, meta-genre markers and general characteristics
Антоніна Аністратенко   +1 more
doaj   +1 more source

Text types in a new medium : the first newspapers (1609) [PDF]

open access: yes, 2009
The first printed newspapers in the modern sense of the word appeared in the seventeenth century. They were weekly publications which contained regular reports by correspondents from all over Europe, mainlyon political matters. Although the new medium as
Fritz, Gerd
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Realising the potential of the family history in risk assessment and primary prevention of coronary heart disease in primary care: ADDFAM study protocol

open access: yesBMC Health Services Research, 2009
Background Coronary heart disease (CHD) is the leading cause of death in the developed world, and its prevention a core activity in current UK general practice.
Kai Joe   +8 more
doaj   +1 more source

The sword of god: Plague and episcopal authority in the Late Antique West [PDF]

open access: yes
This thesis examines three major historical figures of Early Medieval Europe to discover the attitudes and responses to the plague: Pope Gregory the Great, Gregory of Tours, and the Venerable Bede.
Kenney, Amanda
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Ukraine before Statehood: A Blind Spot in Western European Historiography of/on Europe since 1991?

open access: yesZeitschrift für Ostmitteleuropa-Forschung
This article focuses on the relationship between Ukraine and Europe in historiography. It asks whether Ukraine was a blind spot in Western European historiography on Europe since 1991.
Joachim Berger
doaj   +1 more source

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