Results 51 to 60 of about 472,423 (265)

Bibliographic records reveal trends in Chinese history scholarship: Evidence from library of Congress metadata

open access: yesInformation Research: An International Electronic Journal
Introduction. Books are key research outputs in the humanities, but often poorly indexed in scholarly databases. This paper presents a preliminary analysis of metadata in the Library of Congress (LC) to analyse scholarship on Chinese history.
Kai Li, Wenyi Shang, Yingying Han
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

The Material Culture of Road Safety: Road Safety as Museum Display?

open access: yesJournal of Road Safety, 2009
The museum does not usually spring to mind as a site for road safety promotion but no other institution has so much involvement in collecting and displaying the material culture of motoring and interpreting its history for the general public.
Jennifer Clark
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Writing Histories, Making Nations: A Review Essay

open access: yesStoricamente, 2017
Since the 1990s we have seen an increasing number of studies in the history of national history writing, in the ways in which peoples construct nations through the production of historiography.
Marek Tamm
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Den Judiska Kvinnoklubben (JKK) och de judiska flyktingarna under 1930- och 1940-talen

open access: yesNordisk Judaistik, 2019
In a Swedish context, Jewish women’s experiences and actions have gone unrecorded and unrecognised; most narratives of Swedish Jewish history offer only a partial account of their past.
Malin Thor Tureby
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

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