Results 61 to 70 of about 4,440,832 (298)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Buffon, Jefferson and the theory of New World degeneracy

open access: yesEvolution: Education and Outreach, 2019
In his magnum opus, Natural History: General and Particular, Count Buffon, one of the leading natural historians of the 18th century, argued that all life in the New World, particularly North America, was degenerate—weaker, smaller and feebler—than life ...
Lee Alan Dugatkin
doaj   +1 more source

History entanglement entropy [PDF]

open access: yesarXiv, 2020
A formalism is proposed to describe entangled quantum histories, and their entanglement entropy. We define a history vector, living in a tensor space with basis elements corresponding to the allowed histories, i.e. histories with nonvanishing amplitudes.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

New Directions in the History of Written Culture

open access: yesCulture & History Digital Journal, 2012
This article reviews some new directions in the history of writing practices, concentrating on Western Europe and the Americas in the nineteenth and early twentieth centuries.
Martyn Lyons
doaj   +1 more source

Isogrowth Cosmology (and How to Map the Universe) [PDF]

open access: yesarXiv, 2022
While general relativity ties together the cosmic expansion history and growth history of large scale structure, beyond the standard model these can have independent behaviors. We derive expressions for cosmologies with identical growth histories but different expansion histories, or other deviations. This provides a relation for isogrowth cosmologies,
arxiv  

BRST Quantisation of Histories Electrodynamics [PDF]

open access: yesJ.Math.Phys. 43 (2002) 4801-4818, 2001
This paper is a continuation of earlier work where a classical history theory of pure electrodynamics was developed in which the the history fields have \emph{five} components. The extra component is associated with an extra constraint, thus enlarging the gauge group of histories electrodynamics. In this paper we quantise the classical theory developed
arxiv   +1 more source

Czesław Miłosz’ American Experience in Światło dzienne (Daylight) [PDF]

open access: yes, 2016
Miłosz’s volume Światło dzienne (Daylight, 1953) is conventionally read by critics as the political poetry deeply engaged with history. The article offers a corrective to this traditional reading by interpreting the volume as an interplay of European and
Kołodziejczyk, Ewa
core   +2 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Online Appendix & Additional Results for The Determinants of Social Connectedness in Europe [PDF]

open access: yesarXiv, 2020
In this online appendix we provide additional information and analyses to support "The Determinants of Social Connectedness in Europe." We include a number of case studies illustrating how language, history, and other factors have shaped European social networks. We also look at the effects of social connectedness. Our results provide empirical support
arxiv  

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