Results 61 to 70 of about 434,558 (341)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Hacia una historiografía de la enfermedad: Prácticas, profesiones y enfermos
Memoria y Civilización, 2008 The article considers the development of the history of medicine since its institutionalization, in 19th century Europe. The historiographical tendencies that conditioned this development of the branch of learning are analysed.
Pilar León Sanz
doaj
Writing Histories, Making Nations: A Review Essay
Storicamente, 2017 Since the 1990s we have seen an increasing number of studies in the history of national history writing, in the ways in which peoples construct nations through the production of historiography.
Marek Tamm
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
La “potenza del negativo” come destino dell’Europa: un libro di Biagio de Giovanni [PDF]
Democrazia e Diritti SocialiIn this contribution we analyze the constitutive connection of Europe and philosophy in the thought of Biagio de Giovanni, within a properly ‘ontology’ field, according to a ‘fundamental speculative figure’ which is articulated in an ‘ontology of being ...
Antonio Luongo
doaj
Den Judiska Kvinnoklubben (JKK) och de judiska flyktingarna under 1930- och 1940-talen
Nordisk Judaistik, 2019 In a Swedish context, Jewish women’s experiences and actions have gone unrecorded and unrecognised; most narratives of Swedish Jewish history offer only a partial account of their past.
Malin Thor Tureby
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A genetic probe into the ancient and medieval history of Southern Europe and West Asia
Science, 2022 Iosif Lazaridis +204 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source