Results 71 to 80 of about 2,077,438 (389)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Text types in a new medium : the first newspapers (1609) [PDF]

open access: yes, 2009
The first printed newspapers in the modern sense of the word appeared in the seventeenth century. They were weekly publications which contained regular reports by correspondents from all over Europe, mainlyon political matters. Although the new medium as
Fritz, Gerd
core  

A Short History of Urban Forestry in Europe

open access: yesArboriculture & Urban Forestry, 1997
In Europe, more attention is being given to the concept of urban forestry. However, it is applied more to forests under a strong urban influence than to urban greenspace at large.
C. Konijnendijk
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

May 1968 Protests in France in the Collective Memory of the European Commission Politicians

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения
Introduction. The May 1968 protests are an important place of remembrance in the history of Europe. Methods and materials. The author uses the methods of studying collective memory to analyze the image of the May protests in the collective memory ...
Nikita Bulavintsev
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Hacia una historiografía de la enfermedad: Prácticas, profesiones y enfermos

open access: yesMemoria y Civilización, 2008
The article considers the development of the history of medicine since its institutionalization, in 19th century Europe. The historiographical tendencies that conditioned this development of the branch of learning are analysed.
Pilar León Sanz
doaj  

Writing Histories, Making Nations: A Review Essay

open access: yesStoricamente, 2017
Since the 1990s we have seen an increasing number of studies in the history of national history writing, in the ways in which peoples construct nations through the production of historiography.
Marek Tamm
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

La “potenza del negativo” come destino dell’Europa: un libro di Biagio de Giovanni [PDF]

open access: yesDemocrazia e Diritti Sociali
In this contribution we analyze the constitutive connection of Europe and philosophy in the thought of Biagio de Giovanni, within a properly ‘ontology’ field, according to a ‘fundamental speculative figure’ which is articulated in an ‘ontology of being ...
Antonio Luongo
doaj  

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