Results 91 to 100 of about 3,197,456 (294)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Prospective History Teachers' Experiences in Place-Based Education: A Qualitative Study on the Development of Social-Emotional Skills

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan
21st-century education requires teachers to be not only cognitively competent but also to have mature social-emotional skills, especially for prospective history teachers in facilitating historical empathy and managing sensitive discussions.
Bonita Padang, Dyah Kumalasari, Malik Salim   +2 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Measuring Historical Thinking Ability: A Quantitative Study of Students on The Indonesia-Malaysia Border, Sambas Regency, West Kalimantan

Yupa: Historical Studies Journal
This study aims to describe the process of history teaching and the HT skills of high school students in the Indonesia-Malaysia border region. The method used is quantitative with a descriptive case study approach.
Haris Firmansyah, Astrini Eka Putri
doaj   +1 more source

Fully supervised training of Gaussian radial basis function networks in WEKA [PDF]

, 2014
Radial basis function networks are a type of feedforward network with a long history in machine learning. In spite of this, there is relatively little literature on how to train them so that accurate predictions are obtained.
Frank, Eibe
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Using online primary sources to foster historical thinking [PDF]

, 2016
This paper describes an ongoing initiative to enhance learner digital literacies by fostering historical thinking using digitized primary sources.
Brunton, James, Farrell, Orna
core  

Organizational learning in a college of nursing: A learning history

Nurse Education Today, 2018
College of nursing leaders can foster organizational learning as a means of achieving their desired organizational outcomes. Organizational learning has not previously been studied in colleges of nursing, leaving college administrators and faculty little guidance as they strive to improve outcomes in their own colleges.The purpose of this study was to ...
Bret Lyman, Lisa A. Cowan, Hannah C. Hoyt   +2 more
openaire   +3 more sources

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Transformation of History Education Based on Local Wisdom to Foster Historical Awareness in Generation Z

Jurnal Iqra': Kajian Ilmu Pendidikan
This research aims to analyze the transformation of history learning based on local wisdom in fostering historical awareness in generation Z at MA Matik Al Uswah Banyuwangi.
Agus Mursidi
doaj   +1 more source