Results 51 to 60 of about 587,223 (263)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Model Pembelajaran Interaktif dan Keterampilan Sosial terhadap Hasil Belajar Kognitif Siswa pada Pembelajaran Sejarah di SMA

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2019
: This research aims to determine the effect of interactive learning models on student cognitive learning outcomes, determine the effect of social skills on students 'cognitive learning outcomes, and determine the effect of interaction between ...
Ririk Ajeng Alfianti, Blasius Suprapta, Endang Sri Andayani   +2 more
doaj   +1 more source

Ako. Learning From History?

, 2022
Introduction of the issue Vol 29 (2022): Public History in Aotearoa New ...
McKergow F, Watson G, Littlewood D, Neill C   +3 more
openaire   +4 more sources

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Efektivitas Model Pembelajaran Flipped Classroom terhadap Peningkatan Motivasi Belajar Siswa pada Mata Pelajaran Sejarah di SMAN 2 Bandung

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan
Background of this research is low student motivation in history lesson. This is caused by monotonous learning, which makes students bored.This study aims to determine how effective the flipped classroom model is in enhancing learning motivation ...
Muhammad Juraisy Haq, Deni Kurniawan, Dadi Mulyadi   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peran Situs Sejarah melalui Pendekatan Project Based Learning dalam Meningkatkan Pemahaman Pembelajaran Sejarah Peserta Didik MAS Nurussa’adah Jakarta Selatan

Jurnal Humanitas: Katalisator Perubahan dan Inovator Pendidikan
The role of historical sites in history learning has great potential to improve students' understanding through contextual direct learning experiences. However, in reality, history learning in schools is still dominated by conventional methods that are ...
Manda Azzahra, Rudy Gunawan
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source