Results 101 to 110 of about 1,239,693 (328)

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Systems engineering and integration and management for manned space flight programs [PDF]

open access: yes
This paper discusses the history of SE&I management of the overall program architecture, organizational structure and the relationship of SE&I to other program organizational elements.
Morris, Owen
core   +1 more source

Book review: Ordnance: war + architecture & space [PDF]

open access: yes, 2013
Ordnance: War + Architecture & Space investigates how strategies of warfare occupy and alter built and other landscapes. Ranging across the modern period from the eighteenth century to the present day, the book presents a series of case-studies from the ...
Ferrari, Lorenzo
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Conservation and modern architecture. Fortune and misfortune of the School of Mathematics at Rome University (G. Ponti, 1932-1935) [PDF]

open access: yes, 2015
The framework of the Italian restoration doctrine is based on the reception and transmission of the memory of the past. However, interventions in modern architecture represent a radical drift in the sense that they mostly consist of reconstructions ...
SALVO, Simona Maria Carmela
core  

Speaker-Sensitive Dual Memory Networks for Multi-Turn Slot Tagging

open access: yes, 2017
In multi-turn dialogs, natural language understanding models can introduce obvious errors by being blind to contextual information. To incorporate dialog history, we present a neural architecture with Speaker-Sensitive Dual Memory Networks which encode ...
Kim, Young-Bum   +2 more
core   +1 more source

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun   +95 more
wiley   +1 more source

The Techno-aesthetical Architectural Dilemma: Paradigmatic Histories of Reinforced Concret

open access: diamond, 2020
Khaoula HANNACHI   +2 more
openalex   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou   +12 more
wiley   +1 more source

Leon Battista Alberti and the Concept of Lineament [PDF]

open access: yes, 2011
A core idea in the architectural theory of Leon Battista Alberti, as expressed in the De re aedificatoria, is the distinction between “lineament,” the line in the mind of the architect, and “matter,” the material presence of the building.
Hendrix, John S
core   +1 more source

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