Results 61 to 70 of about 4,530,314 (306)

Federalism in Middle Europe: a model for a future European education system? [PDF]

open access: yes, 2001
The article discusses the principle of federalism as a potential institutional principle of the future education system in Europe. It reminds of the strengths and weaknesses of federalism in the history of Central Europe and clarifies the differences ...
Waterkamp, Dietmar
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Aesthetic and Formative values of Mural Painting Scenes in Ancient Egyptian Art As a Suggested Introduction to Appreciating Contemporary Wooden Murals

open access: yesJournal of Architecture, Art & Humanistic Science
The research deals with studying the aesthetic and plastic values of mural scenes in ancient Egyptian art and using them as a suggested entry point for appreciating contemporary wooden murals, by clarifying the importance of wall painting in general and ...
Dr. Dalia Mohamed Mahmoud Sharaf Lecturer of Art History and Appreciation, Department of Art Education, Faculty of Specific Education, Alexandria University   +2 more
doaj   +1 more source

Reassessing 1960s philosophy of the curriculum [PDF]

open access: yes, 2005
A prominent thesis of British philosophy of education in the 1960s was that the pursuit of different forms of knowledge is central to education. The fact that the thesis is difficult to justify philosophically raises questions about its historical ...
White, John
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Quem somos nós, professores de matemática?

open access: yesCadernos Cedes
Ao saber quem são seus avôs, bisavôs e mesmo tataravôs profissionais, o professor de matemática passa a ver o trabalho de seus colegas contemporâneos, e seu próprio fazer docente, de outro modo. Dá a seu ofício uma dimensão histórica.
Wagner Rodrigues Valente
doaj   +1 more source

The historical research method in Al-Thaalabi [PDF]

open access: yesآداب الرافدين, 1987
Since the end of the third and early fourth centuries AH - the tenth century AD, a group of court writers and court regrets entered the field of historical notation, and coloring history became one of the tasks of employees and rebels of the court.
Ghder AlDory, Thamer Mohamed
doaj   +1 more source

21st Century Ergonomic Education, From Little e to Big E [PDF]

open access: yes, 2014
Despite intense efforts, contemporary educational systems are not enabling individuals to function optimally in modern society. The main reason is that reformers are trying to improve systems that are not designed to take advantage of the centuries of ...
Barsky, Constance K.   +1 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy