Results 101 to 110 of about 178,354,408 (309)

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

The Political Economy of Ideas:Historical Materialism and the History of Ideas

open access: yes
In this essay I outline the relevance of a historical materialist approach to the study of intellectual history, drawing on Karl Marx’s critique of political economy.
Flohr, Mikkel
core  

Lexicon of Migrating Ideas in the Slavic Balkans (18th–21st c.). Vol. 10: Subordinate Entries

open access: yes, 2020
Dziesiąty tom obszernej (dziesięcioczęściowej) monografii, opracowanej przez slawistów polskich (przy współpracy uczonych z kilku ośrodków zagranicznych) w ramach grantu NCN OPUS (2014/13/B/HS2/01057).
Szwat-Gyłybowa, Grażyna (red.)   +2 more
core  

The Natural History of Illinois: Illinois State Laboratory of Natural History Bulletin Volume 1 no. 2 [PDF]

open access: yes, 1878
This is the second of a series of publications, issued by authority of the State Board of Education of Illinois, and designed especially to elucidate the natural history of this State. The first number was published in December, 1876, as Bulletin No.
Illinois State Laboratory of Natural History
core  

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

173:poster Towards all-inclusive healthcare allocations

open access: yesBMJ Global Health, 2022
Aksel Braanen Sterri, Albert Didriksen
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Current neuropsychological understanding of consciousness as influenced by antecedent arguments in the philosophy of mind [PDF]

open access: yes, 2013
This paper provides a detailed description of the antecedent influences of philosophy on modern neuropsychological conceptions of consciousness. A brief philosophical history of consciousness in the form of several famous arguments is illustrated, which ...
Kerr, Jeff
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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