Results 81 to 90 of about 2,765,941 (307)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Complexity, parallel computation and statistical physics
, 2005 The intuition that a long history is required for the emergence of complexity in natural systems is formalized using the notion of depth. The depth of a system is defined in terms of the number of parallel computational steps needed to simulate it. Depth
Machta, J.
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The American Historical Review, 1968 PROBABLY almost everyone attending the Annual Meetings of the American Historical Association, and even more this year's combined North American meeting, will derive encouragement from seeing historical scholarship actively represented by such a strong professional corps.
openaire +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Bossy matrons and forced marriages: Talmudic confrontationalism and its philosophical significance
Open Philosophy, 2020 This article introduces the confrontational theology of the rabbinic literature of late antiquity by means of a well-known, yet ill-understood legend.
Fisch Menachem
doaj +1 more source
, 2018 Exoplanet surface imaging, cartography and the search for exolife are the next frontiers of planetology and astrophysics. Here we present an over-view of ideas and techniques to resolve albedo features on exoplanetary surfaces.
A Carbognani +37 more
core +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Indian Physics: Outline of Early History [PDF]
, 2003 Historians of science are generally unaware of the contributions of India to physics. The main reason for this is that very little research has been done on the subject in the recent past, a consequence of the fact that there are few history of science ...
Kak, Subhash
core +1 more source