Results 61 to 70 of about 2,947,430 (350)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Personal Utopia: The “Good Life” in Popular Religion and Literature in Contemporary Sweden
This article examines the discourse of the “good life” in popular religion and literature in contemporary Sweden. The results indicate thnew spiritual movements (e.g.
Daniel Enstedt, Kristina Hermansson
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The production of ideas: Notes on Austrian intellectual history from Bolzano to Wittgenstein [PDF]
This paper takes the form of a series of sketches of 19th century Austrian political and intellectual history, allied with a number of more general reflections designed to contribute to our understanding of some of the peculiar characteristics of ...
Smith, Barry
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The postcommunist concept of transition, as it was in use during the 1990s and early 2000s, is analyzed from the viewpoint of its intellectual prehistory.
Kristian Petrov
doaj
From AGS-SPS and Onwards to the LHC
I review the history of the efforts using heavy ion collisions to make new forms of matter. I discuss both the development of the theoretical ideas about such new forms of matter, as well the past, present and planned experimental efforts.
McLerran, Larry
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Friedrich List's Adam Smith historiography and the contested origins of development theory [PDF]
Friedrich List's National System of Political Economy continues to be positively received in IPE, where it is treated as a seminal text in development theory.
Watson, Matthew
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

