Results 91 to 100 of about 6,382,615 (401)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

The History of Polyarchion (πολυάρχιον), John Chrysostom’s Illness, and Access to Medicinal Treatments at the End of Late Antiquity

open access: yesVox Patrum
John Chrysostom’s (c. 347‑407) works are valuable for medical historians because they provide us with a first-hand insight into his health problems and the therapies he was treated with.
Zofia Rzeźnicka, Maciej Kokoszko
doaj   +1 more source

Cardiocentrism in ancient medicines

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2023
History of cardiology starts scientifically in 1628, when William Harvey (1578–1657) published his revolutionary book Extercitatio anatomica de motu cordis et sanguinis in animalibus, where he described “general” circulation, movements and functions of ...
Fabio Zampieri   +2 more
doaj  

Clinical Pharmacology in the UK, c.1950-2000: Industry and Regulation [PDF]

open access: yes, 2008
Annotated and edited transcript of a Witness Seminar held on 25 September 2007. Introduction by Professor Parveen Kumar, Barts and the London School of Medicine and Dentistry, University of London.First published by the Wellcome Trust Centre for the ...
Reynolds, LA, Tansey, EM
core  

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

MD Voldemar Sumberg and the Folk Medicine Collection of the Estonian Museum of Hygiene from the 1920s and 1930s

open access: yesJournal of Ethnology and Folkloristics, 2011
Based on the documents preserved in several museums and archives in Tartu and Tallinn (the Estonian Health Care Museum, the Estonian State Archives, the Estonian Historical Archives, the Estonian Folklore Archives and the Estonian National Museum), the ...
Ave Tupits
doaj  

Distributed Representation for Traditional Chinese Medicine Herb via Deep Learning Models [PDF]

open access: yesarXiv, 2017
Traditional Chinese Medicine (TCM) has accumulated a big amount of precious resource in the long history of development. TCM prescriptions that consist of TCM herbs are an important form of TCM treatment, which are similar to natural language documents, but in a weakly ordered fashion.
arxiv  

History of Medicine: Health, Medicine and Disease in the Eighteenth Century.

open access: yesThe British journal for eighteenth-century studies, 2011
This article surveys anglophone scholarship in the history of medicine over the past decade or so. It selectively identifies and critically evaluates key themes and trends in the field.
J. Andrews
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy