Results 51 to 60 of about 3,662,534 (344)
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
The Rhesus Factor and Disease Prevention [PDF]
First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2004. ©The Trustee of the Wellcome Trust, London, 2004. All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/Annotated ...
Christie, DA, Tansey, EM, Zallen, DT
core
This is the edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, London, on 6 June 2000. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2001.©The Trustee of the Wellcome ...
Christie, DA, Tansey, EM
core
Medical Expertise, Bodies, and the Law in Early Modern Courts [PDF]
Commissioned 3000-word essay for the section Focus of ISIS, the leading journal in the history of science internationally. This section aims to present innovative historiographical approaches, in this case in relation to the theme 'Science and Law ...
De Renzi, Silvia
core +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
David Stove reviews Selwyn Grave's History of Philosophy in Australia, and praises philosophers for thinking harder about the bases of science, mathematics and medicine than the practitioners in the field. The review is reprinted as an appendix
Stove, D. C.
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Decline and decadence in Iraq and Syria after the age of Avicenna? : ʿAbd al-Laṭīf al-Baghdādī (1162–1231) between myth and history [PDF]
‘Abd al-Laṭīf al-Baghdādī’s (d. 1231) work Book of the Two Pieces of Advice (Kitāb al Nasīḥatayn) challenges the idea that Islamic medicine declined after the twelfth century AD.
Joosse, Nanne Pieter George+1 more
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source