Results 101 to 110 of about 317,424 (303)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Spies, Sight, Splints & Snow : Family Friendly History of Science, Technology & Medicine

open access: yes, 2015
Public engagement with science, technology and medicine in World War
Hobbs, Laura Kate, Hobbs, L.K.
core  

World Association for the History of Veterinary Medicine 44th International Congress : 27-29 February 2020, The Farm Inn Hotel and Conference Centre, Pretoria, South Africa : proceedings

open access: yes, 2020
Presentation delivered at the 44th International Congress of the World Association for the History of Veterinary Medicine held from the 27-29 of February 2020 at The Farm Inn Hotel and Conference Centre, Pretoria, South AfricaThis paper emphasizes the ...
Welk-Joerger, Nicole
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Making lives under closure : birth and medicine in Palestine's waiting zones [PDF]

open access: yes, 2006
Thesis (Ph. D. in History, Anthropology, and Science, Technology and Society (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2006.Includes bibliographical references (p.
Wick, Livia
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The development of sports medicine in Twentieth-century Britain

open access: yes, 2009
Sports medicine has grown in importance and visibility in recent years, yet as a discipline it struggled to gain broad recognition within the medical profession from c.1952 until specialty status was granted in 2005.

core  

The Association Between Coffee and Tea Consumption During Pregnancy and Preterm Delivery: Case–Control Study

open access: yesJournal of Multidisciplinary Healthcare, 2020
Amer Mahmoud Sindiani,1 Yousef Khader,2 Zouhair Amarin1 1Department of Obstetrics and Gynecology, Jordan University of Science and Technology, Irbid, Jordan; 2Department of Public Health and Community Medicine, Jordan University of Science and Technology,
Sindiani AM, Khader Y, Amarin Z
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

History of Science

open access: yes
History of Science is devoted to the history of science, medicine and technology from earliest times to the present day. Articles discussing methodology, and reviews of the current state of knowledge and possibilities for future research, are especially ...
GUAGNINI, ANNA
core  

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