Results 91 to 100 of about 317,424 (303)

The evolution of psychotherapy: from Freud to prescription digital therapeutics

Frontiers in Psychiatry
The evolution of psychotherapeutic treatments from Freud to digitally administered evidence-based treatments reflects a history of progressive advance.
John P. Docherty, Brett M. Colbert
doaj   +1 more source

Effect of 2% Topical Lidocaine Gel on Discomfort from Electrical Stimulation During Nerve Conduction Studies- A Prospective Double-Blind Placebo-Controlled Study

Local and Regional Anesthesia, 2023
Kefah Al-Hayk,1 Mahmoud M Smadi,2 Lina M Elsalem,3 Ahmed Yassin,1 Suha Aqaileh,1 Deema H Obiedat,1 Ahmad Kefah Al-Hayk,4 Majdi Al Qawasmeh1 ,† Raid Kofahi,1 Khalid El-Salem1 1Neurology Department, Faculty of Medicine, Jordan University of Science and ...
Al-Hayk K, Smadi MM, Elsalem LM, Yassin A, Aqaileh S, Obiedat DH, Al-Hayk AK, Al Qawasmeh M, Kofahi R, El-Salem K   +9 more
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

History of Dialysis in the UK: c.1950-1980

, 2009
Annotated and edited transcript of a Witness Seminar held on 26 February 2008. Introduction by Professor John Pickstone.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2009.©The Trustee of the Wellcome Trust, London, 2009.
Crowther, SM, Reynolds, LA, Tansey, EM
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Dilemmas in fetal medicine: premature application of technology or responding to womens choice?

, 2006
Copyright @ 2006 The Author.It is argued that innovative health technologies (IHTs) may be changing the roles of both patients and health practitioners, and raising new issues, including ethical, legal and social dilemmas.
Williams, C, Clare Williams
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Epilogue: Textiles, Technology, and Gender in China

, 2013
The seminal research of Francesca Bray (1997) and Susan Mann (1992, 1997) on women and domestic work, especially textiles, have inspired a generation of new research in cultural history and art history, and the articles presented in this special issue ...
Ko, Dorothy
core  

Reinventing bodies and practice in medical education [PDF]

, 2004
Thesis (Ph. D. in History and Social Study of Science and Technology (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, June 2004."May 2004."Includes bibliographical references (p.
Prentice, Rachel
core  

Rare Occurrence of Left Ampullary Ectopic Pregnancy After Ligation of the Left Fallopian Tube: A Case Report

International Journal of Women's Health, 2023
Xue Ke,1 Li He,2 Jia-Feng Zheng,1 Yong-Hong Lin,1 Fang Wang1 1Department of Reproductive Medicine, Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic ...
Ke X, He L, Zheng JF, Lin YH, Wang F
doaj