Results 141 to 150 of about 5,700,334 (377)
Fall 2016 - HIPS Newsletter [PDF]
https://nsuworks.nova.edu/cahss_hips_newsletter/1002/thumbnail ...
Department of History and Political Science
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Introduction: Special Issue ‘Translating and translations in the history of science’
Bettina Dietz
semanticscholar +1 more source
Section on Historical and Philological Sciences (L) and the History of Science Society [PDF]
Sarah G. Mayer, Henry R. Viets
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Combining Theory and Practice in the Teaching of Science Institutions: A Collaborative Program between the City University of New York and the American Museum of Natural History [PDF]
The National Science Education Standards contain several mandates that share the use of alternative and creative experiences in the teaching of science at all levels.
Espinoza, F.
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
History of Oceanography, Number 12 [PDF]
Commission of Oceanography, Division of History of Science, International Union of the History and Philosophy of Science
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source