Results 61 to 70 of about 5,700,334 (377)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Atoll research bulletin. [PDF]

, 2005
no.531-542 ...
National Museum of Natural History (U.S.), National Research Council (U.S.). Pacific Science Board., Smithsonian Institution., Smithsonian Institution. Press, United States. Bureau of Sport Fisheries and Wildlife.   +4 more
core   +1 more source

THE LIBRARY OF THE TECHNICAL UNIVERSITY OF GDANSK IN BREMEN

TASK Quarterly, 2002
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ANDRZEJ JANUSZAJTIS
doaj  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Rational Reconstruction Reconsidered [PDF]

, 2010
Here is a dilemma concerning the history of science. Can the history of scientific thought be reduced to the history of the beliefs, motives and actions of scientists?
Nanay, Bence
core  

Internal History versus External History [PDF]

, 2017
The aim of this paper is to generalize a pair of concepts that are widely used in the history of science, in art history and in historical linguistics – the concept of internal and external history – and to replace the often very ...
Aunger, Baxandall, Baxandall, Becker, Bence Nanay, Bowler, Bowler, Bowler, Brown, Bulmer, Cookson, Darwin, Davidson, Davis, Davis, Dawkins, Dawkins, Dawkins, Dennett, Dennett, Dennett, Distin, Elkana, Gould, Hauser, Holton, Holton, Hull, Hull, Kitcher, Kuhn, Kuhn, Latour, Laudan, Mayr, Mayr, McMullin, Musil, Palmer, Popper, Popper, Popper, Popper, Richerson, Sperber, Summers, Summers, Toulmin, Toulmin, Vorzimmer, White, Wölfflin   +51 more
core   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Jordan's Derivation of Blackbody Fluctuations [PDF]

, 2017
The celebrated Dreimännerarbeit by Born, Heisenberg and Jordan contains a matrix-mechanical derivation by Jordan of Planck’s formula for blackbody fluctuations.
Bacciagaluppi, G., Crull, Elise, Maroney, Owen, Sub History and Philosophy of Science, History of Science   +4 more
core   +2 more sources

SCIENTISTS IN OLD GDANSK: 19th AND 20th CENTURIES

TASK Quarterly, 2001
-
ANDRZEJ JANUSZAJTIS
doaj  

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source