Results 61 to 70 of about 1,469,531 (356)

SCIENTISTS IN OLD GDANSK: PREHISTORY AND 16th CENTURY

TASK Quarterly, 2001
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ANDRZEJ JANUSZAJTIS
doaj  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Questioning Nature in Late Middle Ages. A History of Method, Praxis and Innovation

Medievalia, 2022
This essay traces the interconnections between method, praxis and innovation with their epistemological consequences at the end of the Middle Ages. In the wake of scholastic natural philosophy, this vibrant process marks a milestone in the history of ...
Giovanni Patriarca
doaj   +2 more sources

History of Science [PDF]

Nature, 1972
The Science of Matter: a Historical Survey . Edited By M. P. Crosland. Pp. 440. (Penguin: Harmondsworth, 1971.) 70p. Steps in the Scientific Tradition: Readings in the History of Science . Edited by R. S. Westfall and V. E. Thoren. Pp. xii + 544. (Wiley: New York and London, October 1971.) £3.50 cloth; £1.75 paper.
openaire   +1 more source

Ten Years of Research on History of Science (Physics): A Bibliometric Analysis

, 2021
Eva Ayu Yanuarti, Nadi Suprapto
openalex   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

In Memoriam: Rein Vihalemm (1938–2015) [PDF]

Acta Baltica Historiae et Philosophiae Scientiarum, 2015
University of Tartu, Faculty of Philosophy of University of Tartu, Institute of Philosophy and Semiotics of University of Tartu, Estonian Association for the History and Philosophy of Science   +3 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source