Results 71 to 80 of about 1,469,531 (356)

Wikipedia as a tool for contemporary history of science: A case study on CRISPR. [PDF]

open access: yesPLoS One, 2023
Benjakob O   +9 more
europepmc   +1 more source

Science and History of Science

open access: yesTransversal: International Journal for the Historiography of Science, 2018
In the present article, we discuss the specificity of the object of the history of science as an autonomous and interdisciplinary field of studies by nature and origin, placed at the interface of history, epistemology and science, and focus on some key historiographical views. Within this context, Georges Canguilhem stands out for contributions such as
Ferraz, Márcia H. M.   +2 more
openaire   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

SCIENTISTS IN OLD GDANSK: 17th AND 18th CENTURIES

open access: yesTASK Quarterly, 2001
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ANDRZEJ JANUSZAJTIS
doaj  

A rota dos estudos sobre a cochonilha em Portugal e no Brasil no século XIX: caminhos desencontrados The route of the studies of cochineal in Portugal and Brazil in the nineteenth century: uncrossed paths

open access: yesQuímica Nova, 2007
For imparting an intense and long-lasting red to fabrics, cochineal remained in high demand during the eighteenth and nineteenth centuries. This period witnessed, accordingly, several initiatives aimed at producing the precious dye: publication of ...
Márcia Helena Mendes Ferraz
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The National Institute for Scientific Research (INIC): Pathway and Influence in Portuguese Science Policy (1976-1992)

open access: yesHoST, 2019
My Ph.D research project aims at writing the history of the Portuguese National Institute for Scientific Research (Instituto Nacional de Investigação Científica, INIC) (1976-92). Although INIC is an important institutional actor in the development of the
Soares Hugo
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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