Results 71 to 80 of about 5,700,334 (377)

Vestiges of the history of popular science [Essay Review] [PDF]

open access: yes, 1995
Robert Chambers, Vestiges of the Natural History of Creation and Other Evolutionary Writings, ed. James A. Secord. Chicago: University of Chicago Press. 1994. Pp. xlviii, vi, 390, viii, 254. US$ 19.95 PB.
Topham, J.R.
core  

How can history of science matter to scientists? [PDF]

open access: yes, 2008
History of science has developed into a methodologically diverse discipline, adding greatly to our understanding of the interplay between science, society, and culture.
Laubichler, Manfred   +2 more
core   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Hume, the Philosophy of Science and the Scientific Tradition [PDF]

open access: yes, 2018
Although the main focus of Hume’s career was in the humanities, his work also has an observable role in the historical development of natural sciences after his time.
Slavov, Matias
core   +2 more sources

SCIENTISTS IN OLD GDANSK: PREHISTORY AND 16th CENTURY

open access: yesTASK Quarterly, 2001
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ANDRZEJ JANUSZAJTIS
doaj  

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

The History of Nanoscience and Nanotechnology: From Chemical–Physical Applications to Nanomedicine

open access: yesMolecules, 2019
Nanoscience breakthroughs in almost every field of science and nanotechnologies make life easier in this era. Nanoscience and nanotechnology represent an expanding research area, which involves structures, devices, and systems with novel properties and ...
Samer Bayda   +4 more
semanticscholar   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

In Memoriam: Rein Vihalemm (1938–2015) [PDF]

open access: yesActa Baltica Historiae et Philosophiae Scientiarum, 2015
University of Tartu   +3 more
doaj   +1 more source

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