Results 41 to 50 of about 206,180 (291)

Patients’ and Professionals’ Views on Managing Fibromyalgia

Pain Research and Management, 2013
BACKGROUND: Managing fibromyalgia is a challenge for both health care systems and the professionals caring for these patients, due, in part, to the fact that the etiology of this disease is unknown, its symptoms are not specific and there is no ...
Erica Briones-Vozmediano, Carmen Vives-Cases, Elena Ronda-Pérez, Diana Gil-González   +3 more
doaj   +1 more source

Influence of the practice of physical exercise and healthy eating on the Vigour of university lectures

Frontiers in Sports and Active Living, 2023
IntroductionVigour at work is characterized by high levels of energy and high desire to make an effort at work. This article is the result of a research carried out with university teachers in Spain whose main objective is to show what type and frequency
Montserrat Monserrat Hernández, Ángeles Arjona Garrido, Juan Carlos Checa Olmos, Antonio Casimiro Andújar, Eva María Artés Rodríguez, Darío Salguero García   +5 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

«Standing beneath the window with my Guitar...»: History and Modernity of Spanish Tuna

RUDN Journal of World History, 2012
This article studies Spanish tuna as a centuries-old tradition of student singing accompanied by the playing on traditional music instruments. The authors present the main features of the modern tuna, research and describe the history of its origin and ...
G Aleksandrovna Khimich, A Aleksandrovna Basmanova   +1 more
doaj  

The Demands of Niqabi Women in the Telegram Subaltern Corner Orgullo Niqabi

Social Inclusion, 2020
The present article is about Niqabi women belonging to the private Telegram instant messaging channel Orgullo Niqabi (Spanish for ‘Niqabi Pride’). More specifically, our main objective is to explain what they are demanding, how they articulate their ...
Alexandra Ainz-Galende, Rubén Rodríguez-Puertas   +1 more
doaj   +1 more source

An account on the history of pharmacology in Spain

Pharmacological Research
Here we present an account on the history of pharmacology in Spain. Pharmacology as an independent science in Europe began with the creation of university chairs. Of particular relevance was the appointment in 1872 of Osswald Shmiedeberg as chairman of an Institute of Pharmacology at the University of Strassbourg, Germany. Teófilo Hernando pioneered in
Ana María Aldea-Perona, Jesús Flórez Beledo, Jesús Frías Iniesta, Antonio G. García, Juan Tamargo, Francisco Zaragozá   +5 more
openaire   +3 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Transforming Our World: The Role of Collections in Education for Sustainable Development

Heritage
The TOWCHED project explores how arts and heritage-based educational methodologies can support sustainable development by enhancing key transversal competencies in learners, particularly children and youth.
Mar Gaitán, Alejandra Nieto-Villena, Arabella León, Indra Ramírez, Ester Alba   +4 more
doaj   +1 more source