Results 51 to 60 of about 1,201,984 (318)
Land, 2023 In recent decades, particularly intense changes have occurred in Spanish urban areas. This is the result of demographic and urbanizing transformations that have led to a change in the city model. The predominance of compact forms has been replaced by the
Francisco Cebrián Abellán +2 more
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The Demons of Judas and Mary Magdalene in Medieval Art
Religions, 2022 There are few specific studies on the demonic possession of Judas and Mary Magdalene, especially as regards the representation of these demons in medieval art.
Elena Monzón Pertejo +1 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Development of geology in Spain: a case study of a marginal science
Geologica Acta, 2015 Geology in Spain developed outside the mainstream of major geological ideas. Geology was introduced intothe country when it had already grown mature.
P.F. SANTANACH I PRAT
doaj
Microbiology Spectrum, 2022 We aimed to review strategies for identifying SARS-CoV-2 infection before the availability of molecular test results, and to assess the reporting quality of the studies identified through the application of the STARD guideline. We screened 3,821 articles
Paula Cremades-Martínez +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
«Standing beneath the window with my Guitar...»: History and Modernity of Spanish Tuna
RUDN Journal of World History, 2012 This article studies Spanish tuna as a centuries-old tradition of student singing accompanied by the playing on traditional music instruments. The authors present the main features of the modern tuna, research and describe the history of its origin and ...
G Aleksandrovna Khimich +1 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source