Results 61 to 70 of about 167,702,766 (324)

The Use of GIS and Multicriteria Techniques for the Socio-Spatial Analysis of Urban Areas in Medium-Sized Spanish Cities

Land, 2023
In recent decades, particularly intense changes have occurred in Spanish urban areas. This is the result of demographic and urbanizing transformations that have led to a change in the city model. The predominance of compact forms has been replaced by the
Francisco Cebrián Abellán, Gonzalo Andrés López, Carme Bellet Sanfeliu   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Evaluation of Diagnostic Strategies for Identifying SARS-CoV-2 Infection in Clinical Practice: a Systematic Review and Compliance with the Standards for Reporting Diagnostic Accuracy Studies Guideline (STARD)

Microbiology Spectrum, 2022
We aimed to review strategies for identifying SARS-CoV-2 infection before the availability of molecular test results, and to assess the reporting quality of the studies identified through the application of the STARD guideline. We screened 3,821 articles
Paula Cremades-Martínez, Lucy A. Parker, Elisa Chilet-Rosell, Blanca Lumbreras   +3 more
doaj   +1 more source

Natural history of Sanfilippo syndrome in Spain

Orphanet Journal of Rare Diseases, 2013
BackgroundMucopolysaccharidosis type III (MPS III), or Sanfilippo syndrome, is caused by a deficiency in one of the four enzymes involved in the lysosomal degradation of heparan sulphate.
V. Delgadillo, Maria del Mar O'Callaghan, L. Gort, M. Coll, M. Pineda   +4 more
semanticscholar   +1 more source

Related Health Factors of Psychological Distress During the COVID-19 Pandemic in Spain

International Journal of Environmental Research and Public Health, 2020
Measures to prevent and contain the COVID-19 health crisis include population confinement, with the consequent isolation and interruption of their usual activities.
J. Gómez-Salgado, Montserrat Andrés-Villas, Sara Domínguez-Salas, D. Díaz-Milanés, C. Ruiz-Frutos   +4 more
semanticscholar   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Inequality, poverty, and the Kuznets curve In Spain, 1850-2000 [PDF]

, 2007
In Spain, inequality evolution fits a Kuznets curve. World wars increased inequality but had non-permanent effects. Progressive taxation had no impact until 1980.
Prados de la Escosura, Leandro
core   +2 more sources

Parallel paleogenomic transects reveal complex genetic history of early European farmers

Nature, 2017
Ancient DNA studies have established that Neolithic European populations were descended from Anatolian migrants who received a limited amount of admixture from resident hunter-gatherers. Many open questions remain, however, about the spatial and temporal
Mark Lipson, Anna Szécsényi-Nagy, Swapan Mallick, A. Pósa, Balázs Stégmár, Victoria Keerl, N. Rohland, Kristin Stewardson, M. Ferry, Megan Michel, Jonas Oppenheimer, Nasreen Broomandkhoshbacht, Éadaoin Harney, Susanne Nordenfelt, B. Llamas, B. Mende, Kitti Köhler, K. Oross, M. Bondár, T. Marton, Anett Osztás, J. Jakucs, Tibor Paluch, F. Horváth, Piroska Csengeri, J. Koós, Katalin Sebők, A. Anders, P. Raczky, Judit Regenye, Judit P. Barna, Szilvia Fábián, G. Serlegi, Z. Toldi, Emese Gyöngyvér Nagy, János Dani, Erika Molnár, G. Pálfi, L. Márk, B. Melegh, Zsolt Bánfai, László Domboróczki, J. Fernández-Eraso, J. A. Mujika-Alustiza, Carmen Alonso Fernández, J. Echevarría, Ruth Bollongino, J. Orschiedt, Kerstin Schierhold, H. Meller, A. Cooper, J. Burger, E. Bánffy, K. Alt, C. Lalueza-Fox, W. Haak, D. Reich   +56 more
semanticscholar   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Translation as a novelty in the Colección de los Tratados, Convenios y documentos internacionales of the Marquis of Olivart

Chronotopos, 2020
This paper aims to highlight the relevance of the Colección de los Tratados, Convenios y documentos internacionales of the Marquis of Olivart from a translation history perspective.
José María Castellano Martínez
doaj   +1 more source