Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
‘Padres de la Patria’ and the ancestral past: commemorations of independence in nineteenth-century Spanish America [PDF]
This article examines the civic festivals held in nineteenth-century Spanish America to commemorate independence from Spain. Through such festivals political leaders hoped, in Hobsbawm's words, ‘to inculcate certain values and norms of behaviour by ...
Earle, Rebecca
core
Spas, steamships and sardines : Edwardian package tourism and the marketing of Galician regionalism [PDF]
From 1901 until the First World War, alongside its principal business of shipping rubber and leather to and from the USA and Northern Brazil, Liverpool's Booth Steamship Company (familiarly known as the ‘Booth Line’) ran a portfolio of highly successful ...
Hooper, Kirsty
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Development of geology in Spain: a case study of a marginal science
Geology in Spain developed outside the mainstream of major geological ideas. Geology was introduced intothe country when it had already grown mature.
P.F. SANTANACH I PRAT
doaj
The Role of Emerging Predictive IT Tools in Effective Migration Governance
Predicting mass migration is one of the main challenges for policymakers and NGOs working with migrants worldwide. Recently there has been a considerable increase in the use of computational techniques to predict migration flows, and advances have ...
Cristina Blasi Casagran+3 more
doaj +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Levinas’ notion of neighbor as an approach to understand Pío Baroja, otherness and modern Spain. [PDF]
The Cold War era touched Spain only subtly. Because of the geopolitical situation of Europe during the second half of the 20th century, Spain remained almost isolated from macro politics, attempting impossible alliances with Italian and German fascism ...
Arranz, Iker
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The Noticias de los arquitectos: towards a ‘National’ definition of Spanish architecture [PDF]
The book Noticias de los arquitectos y arquitectura de España desde su Restauración is the first ever history of Spanish architecture published in Spain.
Miriam Cera
doaj
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
'Not just bones': a cultural and political history of mass grave exhumations in Spain [PDF]
In this paper I analyze the exhumations of mass graves of the Spanish Civil War (1936–39) and dictatorship (1939–75) as spaces where processes of attribution of meaning take place, and I’ll propose a provisional thesis on how cultural and political ...
Colaert, Lore
core +1 more source