Results 51 to 60 of about 10,678,443 (277)

Stirling University Pandemic Oral History Project: “A Constructive Response to a Destructive Event” [PDF]

open access: yes, 2022
In this article, the authors reflect on the University of Stirling Pandemic Oral History project. At this point in the project, the organisers had interviewed a wide range of staff members at the University regarding their experiences during the COVID-19
Bowman, Stephen   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Reflective and feedback performances on Thai medical students’ patient history-taking skills

open access: yesBMC Medical Education, 2019
Background Reflective practice (RP) plays a crucial role in encouraging learners to think critically and consciously about their performances. Providing constructive feedback can further enhance RP.
Weeratian Tawanwongsri, Tharin Phenwan
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

An LGBTI-Inclusive Sexual History Taking Standardized Patient Case

open access: yesMedEdPORTAL, 2012
Introduction The lesbian, gay, bisexual, transgender, and intersex (LGBTI) population is disproportionately affected by providers' lack of training, particularly related to the inability to take an LGBTI-inclusive sexual history.
Kristen Eckstrand   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Leading the Way: Teaching Public History for the First Time

open access: yes, 2019
This paper seeks to discuss some challenges and reflections on teaching a public history class for the first time, in a country with little familiarity with public history as a field, and with limited literature in Spanish.
Silva, Bárbara
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ohio History Center Groundbreaking photographs

open access: yes, 1966
Governor James Rhodes used an Ohio-shaped shovel to turn the first earth for the new Ohio History Center, shown here on on August 22, 1966. The Ohio Historical Society (now the Ohio History Connection) moved to the new building, located near the Ohio ...
Ohio History Connection
core  

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