Results 61 to 70 of about 10,678,443 (277)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Children on steps of Ohio History Center
, 1970 This photograph of children on the steps of the Ohio History Center was taken around 1970. At a press conference held in November 10, 1964, Governor James Rhodes announced financing for the construction of a new archives, library, and museum building ...
Ohio History Connection
core
Public History as Graphic History
Graphic History – the telling, teaching and understanding of history through comics – has been growing in classrooms and university spaces for more than two decades. However, in the discipline of history the engagement with comics is still rare.
Gundermann, Christine
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Ohio History Center Dedication Ceremony photograph
, 1970 This 9.5" x 6.5" (24.13 x 16.51cm) photograph of the dedication of the Ohio History Center, the new home of the Ohio Historical Society (now the Ohio History Connection), was taken on August 23, 1970.
Ohio History Connection
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Practical Guide to Clinical Medicine (Out of Print)
MedEdPORTAL, 2007 This resource is a comprehensive website that offers detailed reviews of most aspects of the physical examination, including description of exam maneuvers, pictures and video of selected abnormal findings, links to other resources, and a review of ...
Charlie Goldberg
doaj +1 more source
Battle flags hanging in Ohio History Center plaza
, 1970 Photograph of Ohio's Battle Flag collection hanging in the plaza of the Ohio History Center in Columbus, Ohio, ca. 1970. The flags were displayed on the Center’s plaza level from the time the building opened in 1970 through the late 1980s, when they were
Ohio History Connection
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source