Results 61 to 70 of about 927,236 (300)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Survey on the Status and the Importance of Initial History Taking in Dental Clinics in S Area

open access: yes치위생과학회지, 2020
Background: A comprehensive history taking at the first visit could be an important start of treatment. This study investigated the current status of the initial history taking for dental patients in S area, and the implementation and importance of the ...
Do-Seon Lim   +3 more
doaj   +1 more source

Sociocultural Women's Health Standardized Patient Case and Student Guide

open access: yesMedEdPORTAL, 2011
Introduction The Sociocultural Women's Health Standardized Patient (SP) exercise is designed primarily for third-year medical students, but can also be utilized by other health professions students learning the skills of incorporating a patient's ...
Carrie Bernat   +8 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Neurological history both twinned and queried by generative artificial intelligence

open access: yesFrontiers in Medicine
Background and objectivesWe propose the use of GPT-4 to facilitate initial history-taking in neurology and other medical specialties. A large language model (LLM) could be utilized as a digital twin which could enhance queryable electronic medical record
Jung-Hyun Lee   +12 more
doaj   +1 more source

Reflective and feedback performances on Thai medical students’ patient history-taking skills

open access: yesBMC Medical Education, 2019
Background Reflective practice (RP) plays a crucial role in encouraging learners to think critically and consciously about their performances. Providing constructive feedback can further enhance RP.
Weeratian Tawanwongsri, Tharin Phenwan
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Evaluation of Children\'s Appendicitis Score Compared With Pediatric Appendicitis Score in Diagnosis of Pediatric Appendicitis

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2020
Introduction: Identification and promotion of diagnostic methods has been a continuous effort to reduce disease and its complications and reduce costs associated with treatment.
Mohammad Khaasteh   +5 more
doaj  

An LGBTI-Inclusive Sexual History Taking Standardized Patient Case

open access: yesMedEdPORTAL, 2012
Introduction The lesbian, gay, bisexual, transgender, and intersex (LGBTI) population is disproportionately affected by providers' lack of training, particularly related to the inability to take an LGBTI-inclusive sexual history.
Kristen Eckstrand   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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