Results 71 to 80 of about 10,678,443 (277)
A Guide to taking a sexual history [PDF]
This guide offers a framework for discussing sexual health issues to help complete the overall picture of your patient\u2019s health. Sexual health can greatly impact overall quality of life.
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Ohio Historical Society Communication Exhibit photograph
, 1970 This photograph documents visitors to the Ohio Historical Society's exhibit on communication. The exhibit was one of the first to open in the new Ohio History Center in 1970. The photograph measures 9.5" x 7.5" (24.13 x 19.05 cm). Founded in 1885, the
Ohio History Connection
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
World War exhibit at Ohio State Museum
, 1940 This photograph shows the "Ohio in the Wars" room at the Ohio State Museum. Seen browsing the exhibit are Dr. William Overman, Curator of History, and Miss Mary Poster, a member of the museum staff.
Ohio History Connection
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Ohio Historical Center Doughboy statue
, 1970 This statue of a World War I American soldier by sculptor Bruce Wilder Saville sits on the lawn of the Ohio History Center in Columbus, Ohio. Saville, a professor at The Ohio State University, cast the scuplture, named "The Victorius Doughboy" in 1924 to
Ohio History Connection
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Acute Ataxia in Children – A Series of Cases to Emphasize the Clinical Approach
MedEdPORTAL, 2011 Introduction This module was developed to help medical students, residents, and fellows learn how to approach the evaluation of children with acute ataxia.
Maria Weimer, Robin English
doaj +1 more source