Results 191 to 200 of about 655,391 (262)

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Unconventional Biexciton Dynamics in Superradiant Perovskite Quantum Dots Driven by Many‐Body Correlations

open access: yesAdvanced Materials, EarlyView.
Single‐particle spectroscopy and variational quantum Monte Carlo simulations reveal that strong many‐body correlations fundamentally alter biexciton radiative recombination in weakly confined CsPbBr3 quantum dots. Intra‐ and inter‐exciton correlations reverse the conventional lifetime hierarchy, yielding biexcitons with longer radiative lifetimes than ...
Chenglian Zhu   +11 more
wiley   +1 more source

Iterative Selection of DNA Nanostructures for Cellular Uptake

open access: yesAdvanced Materials, EarlyView.
DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar   +4 more
wiley   +1 more source

Strong Coupling in Bulk Nanoplasmonic Nanoplatelet Perovskite Scintillators

open access: yesAdvanced Materials, EarlyView.
A bulk scintillating nanocomposite is engineered from CsPbBr3 nanoplatelets and Ag nanocubes to support exciton–plasmon strong coupling under X‐ray excitation. The resulting hybrid polaritonic states appear directly in radioluminescence, opening a route toward polariton‐enabled scintillator design beyond conventional Purcell enhancement.
Michal Makowski   +13 more
wiley   +1 more source

Conserved Motifs in the Ligand-Binding Domain of TetR Family Regulators: Identification and Analysis. [PDF]

open access: yesComput Struct Biotechnol J
Kepa M   +13 more
europepmc   +1 more source

Ionic Gating of Liquid‐Crystal‐Like Pteridine Assemblies Enables Tunable Light Scattering

open access: yesAdvanced Materials, EarlyView.
Tunable optical properties emerge through developmentally regulated ionic gating, which transforms disordered, ultraviolet (UV)‐absorbing organelles into concentrically ordered, liquid‐crystal‐like light scatterers. By integrating analyses of pteridine composition, potassium‐dependent assembly, hierarchical ultrastructure, and optical behavior, the ...
Sourabh Bera   +22 more
wiley   +1 more source

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