Results 51 to 60 of about 562,363 (310)
, 2017 My favorite lesson is a statistics exploration using data from Major League Baseball's (MLB) 3000-Hits Club. Students in my introductorystatistics course analyze two 1-variable data sets—career batting average and total career hits—that have significant ...
Matthew Whitney
core +1 more source
Spherical LiZnBO3: Structural, optical and electrochemical properties
Materials Science for Energy Technologies, 2019 Spherical – LiZnBO3 material is synthesized by sol-gel technique and the structural, optical, and electrochemical properties of LiZnBO3 are analyzed. X-ray diffraction result reveals the formation of α-LiZnBO3.
Ragupathi Veena +3 more
doaj +1 more source
Graphene metasurface hits the point
Light: Science & Applications, 2023 Exceptional points pose exceptional difficulties to access and encircle. By simply gating graphene, it is now easier to hit the exceptional point.
Jiazheng Qin +2 more
doaj +1 more source
PLoS Comput. Biol., 2019 Individual instances of cancer are primarily a result of a combination of a small number of genetic mutations (hits). Knowing the number of such mutations is a prerequisite for identifying specific combinations of carcinogenic mutations and understanding
R. Anandakrishnan +3 more
semanticscholar +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Stroke: Vascular and Interventional Neurology, 2023 Introduction The rapid growth of the elderly population, an increase in cardiac disease, and notable use of intracardiac prosthetic devices has led to an increased prevalence of infective endocarditis (IE).
Giana Dawod +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Receptor-Based Pharmacophore Modeling in the Search for Natural Products for COVID-19 Mpro
Molecules, 2021 Considering the urgency of the COVID-19 pandemic, we developed a receptor-based pharmacophore model for identifying FDA-approved drugs and hits from natural products. The COVID-19 main protease (Mpro) was selected for the development of the pharmacophore
Mohd Saeed +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source