Results 41 to 50 of about 562,363 (310)
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu +8 more
wiley +1 more source
Introduction: Process safety is becoming more difficult as requirements increase. When balancing quality, volume, and safety on a budget, major accidents are unavoidable.
Gnanasekara Baburao +4 more
doaj +3 more sources
Background In the highly competitive environment of academic medicine, junior faculty investigators face high attrition rates due to challenges in finding effective mentorship, securing grant funding, and obtaining resources to support their career ...
John Paul Spence +4 more
doaj +1 more source
Coronavirus hits former-Soviet countries
The year of 2020 started a new chapter in the development of former-Soviet countries. The coronavirus epidemic, which began in the Chinese city of Wuhan, has spread to affect all countries throughout the world, including the countries of the former ...
S. S. Zhiltsov
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Transitioning novel peptide hits into lead compounds [PDF]
Developing novel peptide hits into lead compounds can be challenging and requires a modified approach compared to small molecules. When screening for hits on difficult drug targets such as orphan G-protein coupled receptors (GPCRs) or ion channels it is
Trim, S., Trim, C.
core
Structural variants (SVs) are one of the significant types of DNA mutations and are typically defined as larger-than-50-bp genomic alterations that include insertions, deletions, duplications, inversions, and translocations.
Asmaa A. Helal +4 more
doaj +1 more source
Drug-target residence times can impact drug efficacy and safety, and are therefore increasingly being considered during lead optimization. For this purpose, computational methods to predict residence times, τ, for drug-like compounds and to derive ...
Daria B. Kokh +8 more
doaj +1 more source
Multi-Dimensional, Multilayer, Nonlinear and Dynamic HITS [PDF]
We introduce a ranking model for temporal multi-dimensional weighted and directed networks based on the Perron eigenvector of a multi-homogeneous order-preserving map.
F. Arrigo, Francesco Tudisco
semanticscholar +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

