Results 31 to 40 of about 562,363 (310)

Hidden oscillations in plain sight: Identification of seismically unresolved red-giant asteroseismic binary candidates

Astronomy & Astrophysics
Context. Light curves of oscillating stars provide valuable insights into the stellar interiors. In some cases, the aperture mask used to extract a light curve can record fluxes from multiple stars.
Choi Jeong Yun, Espinoza-Rojas Francisca, Hekker Saskia   +2 more
doaj   +1 more source

HITS-CLIP in various brain areas reveals new targets and new modalities of RNA binding by fragile X mental retardation protein

Nucleic Acids Research, 2018
Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is due to the functional deficiency of the fragile X mental retardation protein (FMRP), an RNA-binding protein involved in translational regulation of many messenger ...
T. Maurin, K. Lebrigand, S. Castagnola, A. Paquet, Marielle Jarjat, A. Popa, Mauro Grossi, F. Rage, B. Bardoni   +8 more
semanticscholar   +1 more source

Covalent Hits and Where to Find Them.

SLAS discovery : advancing life sciences R & D
Covalent hits for drug discovery campaigns are neither fantastic beasts nor mythical creatures, they can be routinely identified through electrophile-first screening campaigns using a suite of different techniques.
Simon C C Lucas, J. Blackwell, Sarah Hewitt, H. Semple, Benjamin C. Whitehurst, Hua Xu   +5 more
semanticscholar   +1 more source

CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions.

Cancer Discovery, 2016
UNLABELLED CRISPR/Cas9 has emerged as a powerful new tool to systematically probe gene function. We compared the performance of CRISPR to RNAi-based loss-of-function screens for the identification of cancer dependencies across multiple cancer cell lines.
D. Muñoz, Pamela J Cassiani, Li Li, E. Billy, Joshua M. Korn, Michael D. Jones, J. Golji, David A. Ruddy, Kristine Yu, G. McAllister, Antoine de Weck, D. Abramowski, J. Wan, M. Shirley, S. Neshat, Daniel P. Rakiec, Rosalie de Beaumont, Odile Weber, A. Kauffmann, E. Mcdonald, N. Keen, F. Hofmann, W. Sellers, T. Schmelzle, F. Stegmeier, M. Schlabach   +25 more
semanticscholar   +1 more source

Regions where activity to experimental task hits was greater than control task hits.

, 2018
Regions where activity to experimental task hits was greater than control task hits.
Devin Clarke (5329175), Naji Tabet (5329166), Sarah L. King (245546), Jennifer M. Rusted (5329169), Nicholas G. Dowell (5329172), Samuel B. Hutton (5329178), Simon Evans (3273909)   +6 more
core   +1 more source

t437-t2.hits

, 2022
Hits for TREC topic 437.
Ryan Scherle (97132)
core   +1 more source

HITS: characterising well-informed and well-informing nursing professionals [PDF]

, 2023
[ES] Estudio de análisis de redes sociales utilizando el algoritmo de HITS para identificar tanto nodos bien informados como buenos informantes en las redes de consejo o de compartir información desarrolladas por profesionales de enfermería que han ...
Escobar Aguilar, Gema, Martínez Gimeno, María Lara, Ovalle Perandones, María Antonia, Ovalle-Perandones, María-Antonia   +3 more
core   +1 more source

The glide score and FitValues for the of top 23 hits obtained from the virtual hits.

, 2018
The glide score and FitValues for the of top 23 hits obtained from the virtual hits.
Ranajit Nivrutti Shinde (2289166), G. Siva Kumar (5410151), M. Elizabeth Sobhia (472463), Shahbaz Eqbal (5410148)   +3 more
core   +1 more source

Use of a quantitative data report in a hypothetical decision scenario for health policymaking: a computer-assisted laboratory study

BMC Medical Informatics and Decision Making, 2021
Background Quantitative data reports are widely produced to inform health policy decisions. Policymakers are expected to critically assess provided information in order to incorporate the best available evidence into the decision-making process.
Pamela Wronski, Michel Wensing, Sucheta Ghosh, Lukas Gärttner, Wolfgang Müller, Jan Koetsenruijter   +5 more
doaj   +1 more source

Fragment Hits: What do They Look Like and How do They Bind?

Journal of Medicinal Chemistry, 2019
A “fragment hit”, a molecule of low molecular weight that has been validated to bind to a target protein, can be an effective chemical starting point for a drug discovery project.
F. Giordanetto, Chentian Jin, Lindsay Willmore, M. Feher, D. Shaw   +4 more
semanticscholar   +1 more source