Results 31 to 40 of about 956,694 (276)

Non-linear relationship of cell hit and transformation probabilities in a low dose of inhaled radon progenies [PDF]

open access: yes, 2009
Cellular hit probabilities of alpha particles emitted by inhaled radon progenies in sensitive bronchial epithelial cell nuclei were simulated at low exposure levels to obtain useful data for the rejection or support of the linear-non-threshold (LNT ...
Balásházy, Imre   +3 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Spherical LiZnBO3: Structural, optical and electrochemical properties

open access: yesMaterials Science for Energy Technologies, 2019
Spherical – LiZnBO3 material is synthesized by sol-gel technique and the structural, optical, and electrochemical properties of LiZnBO3 are analyzed. X-ray diffraction result reveals the formation of α-LiZnBO3.
Ragupathi Veena   +3 more
doaj   +1 more source

Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-Based Approaches

open access: yesViruses, 2021
Hepatitis B virus (HBV) capsid assembly modulators (CpAMs) have shown promise as potent anti-HBV agents in both preclinical and clinical studies. Herein, we report our efforts in identifying novel CpAM hits via a structure-based virtual screening against
Sameera Senaweera   +7 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Tevatron greatest hits

open access: yesReports on Progress in Physics, 2022
Abstract The Tevatron collider led the World energy frontier program in particle physics during the late 20th and early 21st centuries. During this exciting period the standard model of particle physics was in its final stages of development and the search for physics beyond the standard model became one of the main research topics.
Dmitri Denisov, Costas Vellidis
openaire   +4 more sources

Comparative Analysis Of Zebrafish And Planarian Model Systems For Developmental Neurotoxicity Screens Using An 87-Compound Library [PDF]

open access: yes, 2019
There is a clear need to establish and validate new methodologies to more quickly and efficiently screen chemicals for potential toxic effects, particularly on development. The emergence of alternative animal systems for rapid toxicology screens presents
Collins, Eva-Maria S.   +4 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The self-expanding Symetis Acurate does not increase cerebral microembolic load when compared to the balloon-expandable Edwards Sapien prosthesis: a transcranial Doppler study in patients undergoing transapical aortic valve implantation. [PDF]

open access: yesPLoS ONE, 2014
OBJECTIVES: The aim of this study was to quantify potential differences in count, frequency and pattern of high-intensity transient signals (HITS) during transapical transcatheter aortic valve implantation (TA-TAVI), by comparing the Symetis Acurate TA ...
Gabor Erdoes   +7 more
doaj   +1 more source

Gamma Hadron Separation using Pairwise Compactness Method with HAWC

open access: yes, 2015
The High-Altitude Water Cherenkov (HAWC) Observatory is a ground based air-shower array deployed on the slopes of Volcan Sierra Negra in the state of Puebla, Mexico.
Hampel-Arias, Zigfried   +1 more
core   +1 more source

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