Results 11 to 20 of about 562,363 (310)

Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti‐tumor activity in vivo

EMBO Journal, 2021
Cytotoxic T cells (CTLs) can eliminate tumor cells through the delivery of lethal hits, but the actual efficiency of this process in the tumor microenvironment is unclear. Here, we visualized the capacity of single CTLs to attack tumor cells in vitro and
Roxana Khazen, M. Cazaux, Fabrice Lemaître, Béatrice Corre, Z. Garcia, P. Bousso   +5 more
semanticscholar   +1 more source

The Relationship Between Textbooks’ Teaching Ranks in World Top Universities and Citation, PageRank and HITS Indicators [PDF]

پژوهشنامه علم سنجی, 2019
Purpose: Books are significant scholarly publications which contribute a large part to the diffusion of scholarly findings and aid general knowledge promotion.
Ashraf Maleki, Gavad Abbaspour, Abdolrasool Jowkar, Hajar Sotudeh   +3 more
doaj   +1 more source

Metagenomic nanopore sequencing versus conventional diagnosis for identification of the dieback pathogens of mango trees

BioTechniques, 2022
Dieback is one of the most dangerous fungal diseases affecting mango trees. In this study, nanopore metagenome sequencing of the root-soil samples and infected plant tissues was conducted to identify the fungal pathogens present.
Asmaa H Hassan, Abraam S Bebawy, Mina T Saad, Gamal S Mosaad, Bishoy T Saad, Wafaa N Eltayeb, Khaled M Aboshanab   +6 more
doaj   +1 more source

Multiple Parallel Hits Hypothesis in Nonalcoholic Fatty Liver Disease: Revisited After a Decade

Hepatology, 2020
A decade ago, we hypothesised that multiple parallel hits constitute the pathophysiology of non-alcoholic fatty liver disease (NAFLD). We proposed that hepatic lipotoxicity and multiple events beyond the liver, such as adipose tissue inflammation and ...
H. Tilg, T. Adolph, A. Moschen
semanticscholar   +1 more source

“Tibupoeg Pio” maagia ehk väärtusliku traditsioonilise teksti ootamatust esiletõusust [PDF]

Mäetagused, 2014
The article focuses on the song “Il Pulcino Pio” (in Eng. The Little Chick Cheep), which was released and became a real hit in Italy in 2012, analysing the reasons for its popularity.
Maria Zavjalova
doaj   +1 more source

AERODYNAMIC PERFORMANCE ANALYSIS OF CO-FLOW JET AIRFOIL

International Journal of Aviation, Aeronautics, and Aerospace, 2021
The work in this paper aims to increase the maximum lift coefficient of the airfoil by implementing the co-flow jet concept on NACA 0018 airfoil and also to investigate the performance of co-flow jet (CFJ) airfoil.
C M Vigneswaran, Vishnu Kumar G C
doaj   +1 more source

Myristoyl’s dual role in allosterically regulating and localizing Abl kinase

eLife, 2023
c-Abl kinase, a key signaling hub in many biological processes ranging from cell development to proliferation, is tightly regulated by two inhibitory Src homology domains.
Svenja de Buhr, Frauke Gräter
doaj   +1 more source

Caching with Delayed Hits

Conference on Applications, Technologies, Architectures, and Protocols for Computer Communication, 2020
Caches are at the heart of latency-sensitive systems. In this paper, we identify a growing challenge for the design of latency-minimizing caches called delayed hits.
Nirav Atre, Justine Sherry, Weina Wang, Daniel S. Berger   +3 more
semanticscholar   +1 more source

Integrated dataset of screening hits against multiple neglected disease pathogens. [PDF]

, 2011
New chemical entities are desperately needed that overcome the limitations of existing drugs for neglected diseases. Screening a diverse library of 10,000 drug-like compounds against 7 neglected disease pathogens resulted in an integrated dataset of 744 ...
Clive Yeates, Mansour Nuha R., Ridley, Robert, Simon Townson, Dominique Besson, Yeates, Clive, Townson, Simon, Yeates Clive, Jean-Marc Paris, Geary Timothy, Murthy P. K., Ramirez, Bernadette, Maes, Louis, Ramirez Bernadette, Yousif Fouad, Solomon Nwaka, Van Voorhis Wesley C., Samje, Moses, An Matheeussen, Murthy, PK, Suzanne Gokool, Cho-Ngwa Fidelis, P K Murthy, Timothy Geary, Bickle Quentin, Gokool, Suzanne, Bernadette Ramirez, Fidelis Cho-Ngwa, Geary, Timothy, Paris, Jean-Marc, Paris Jean-Marc, Quentin Bickle, Fakorede, Foluke, Shailja Misra-Bhattacharya, Samje Moses, Moses Samje, Bickle, Quentin, Besson, Dominique, Fouad Yousif, Gokool Suzanne, Louis Maes, Van Voorhis, Wesley C, Yousif, Fouad, Nwaka, Solomon, Maes Louis, Townson Simon, Nwaka Solomon, Wesley C Van Voorhis, Misra-Bhattacharya, Shailja, Ridley Robert, Cho-Ngwa, Fidelis, Robert Ridley, Matheeussen An, Fakorede Foluke, Besson Dominique, Matheeussen, An, Foluke Fakorede, Nuha R Mansour, Mansour, Nuha R, Misra-Bhattacharya Shailja, et al.   +60 more
core   +2 more sources

Potential Second-Hits in Hereditary Hemorrhagic Telangiectasia

Journal of Clinical Medicine, 2020
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder that presents with telangiectases in skin and mucosae, and arteriovenous malformations (AVMs) in internal organs such as lungs, liver, and brain.
C. Bernabéu, P. Bayrak-Toydemir, J. McDonald, M. Letarte   +3 more
semanticscholar   +1 more source