Results 141 to 150 of about 25,225,361 (379)
Alexander O. Pasternak+4 more
doaj +1 more source
Introduction. Chemotherapy of HIV infection remains the only means of treating the disease. The process of development new and improving previously developed drugs is therefore considered a priority.
Lyudmila B. Kalnina+2 more
doaj +1 more source
Objective: To evaluate the efficiencies of the standard α thalassemia screening regimen in human immunodeficiency virus (HIV) infected patients and improve the efficiencies of this screening regimen using new cutoff values.
Sarayot Rareongjai+4 more
doaj +1 more source
Detection of HIV-1-infected cells from patients using nonisotopic in situ hybridization [PDF]
RH Singer+3 more
openalex +1 more source
Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection. [PDF]
Mucosa-associated invariant T (MAIT) cell loss in chronic HIV-1 infection is a significant insult to antimicrobial immune defenses. Here we investigate the response of MAIT cells during acute HIV-1 infection utilizing the RV217 cohort with paired ...
Ananworanich, Jintanat+23 more
core
NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen+13 more
wiley +1 more source
The molecular mechanism of HIV-1 transcriptional elongation regulating latent infection
Human immunodeficiency virus type 1 (HIV-1) is the main causative agent of acquired immunodeficiency syndrome (AIDS), and there is currently no effective cure. Although the existing antiretroviral therapy (ART) can effectively suppress virus replication,
HU Shujing, DENG Kai
doaj +1 more source
HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection. [PDF]
Kent J. Weinhold+5 more
openalex +1 more source
HIV-1 virion assembly at the plasma membrane requires the selective recruitment of the viral RNA genome into nascent viral particles while cellular transcripts are excluded. Kutluay et al. now demonstrate that this is a two-step process in which Gag binds sequentially to different sites on the viral genome.
openaire +3 more sources