Results 141 to 150 of about 24,860,034 (345)
Microtiter format gene quantification by covalent capture of competitive PCR products: application to HIV-1 detection [PDF]
, 1993 Hitoshi Kohsaka +3 more
openalex +1 more source
AntiBMPNN: Structure‐Guided Graph Neural Networks for Precision Antibody Engineering
Advanced Science, EarlyView.AntiBMPNN, a deep learning framework that integrates antibody‐specific 3D data, MPNN, frequency‐based scoring, and AlphaFold 3, achieves superior antibody sequence design. In most cases, it outperforms ProteinMPNN, AntiFold, and AbMPNN in CDR design, demonstrating higher binding affinities and sequence recovery.
Ze‐Yu Sun +13 more
wiley +1 more source
Doravirine and Its Potential in the Treatment of HIV: An Evidence-Based Review of the Emerging Data
HIV/AIDS: Research and Palliative Care, 2020 Alexander E Rock,1 Jeremy Lerner,2 Melissa E Badowski1 1University of Illinois, College of Pharmacy, Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, Chicago, IL 60612, USA; 2University of Illinois, College of Pharmacy ...
Rock AE, Lerner J, Badowski ME
doaj
Advanced Science, EarlyView.This work introduces E‐GeoGNN, a graph neural network framework that systematically encodes molecular structural information through three hierarchical correlation graphs: atom‐bond graph, bond‐angle graph, and angle‐dihedral graph. By incorporating quantum and geometric dual‐scale self‐supervised pretraining, Q‐GEM is proposed, a novel molecular ...
Zhijiang Yang +7 more
wiley +1 more source
Advanced Science, EarlyView.DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan +4 more
wiley +1 more source
Biomolecular Interaction Prediction: The Era of AI
Advanced Science, EarlyView.This review offers a thorough examination of recent progress in deep learning for predicting biomolecular interactions, including those involving proteins, nucleic acids, and small molecules. It covers data processing strategies, representative model architectures, and evaluation metrics, while highlighting current methodological limitations.
Haoping Wang, Xiangjie Meng, Yang Zhang
wiley +1 more source
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
Nature, 1996 T. Dragic +10 more
semanticscholar +1 more source
Advanced Science, EarlyView.Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng +6 more
wiley +1 more source