Results 121 to 130 of about 31,026,669 (309)

Media communication in HIV/AIDS and STI : young people perspectives

, 2011
Background: Although recent developments of antiretroviral drugs for treating HIV/AIDS appear promising, prevention of infection is the only safeguard; and the key factor to preventing infection, be it of HIV or any other sexually transmitted disease, is
Razaghi, Kazem (R20892)
core  

Commercial sex and the spread of HIV in four cities in sub-Saharan Africa. [PDF]

, 2001
OBJECTIVE: To examine whether commercial sex transactions were more common and/or transmission between sex workers and clients more efficient in two African cities with high HIV prevalence (Kisumu, Kenya and Ndola, Zambia) compared with two with ...
Morison, L., Caraël, M, Weiss, HA, Kanhonou, L., Hayes, R. J., Chege, J., Buvé, A, Buvé, A., Abega, S. C., Weiss, H. A., Study Group on Heterogeneity of HIV Epidemics in African Cities, Caraël, M., Chege, J, Kanhonou, L, Abega, SC, Kaona, F., Morison, L, Kaona, F, Hayes, RJ   +18 more
core   +1 more source

HIV-1 tropism [PDF]

Protein & Cell, 2010
Aikichi, Iwamoto, Noriaki, Hosoya, Ai, Kawana-Tachikawa   +2 more
openaire   +2 more sources

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Analysis of genetic polymorphisms and drug resistance mutations in the NS5 region of HCV genome (Flasuviricetes: Amarillovirales: Flaviviridae: Hepacivirus C) in samples obtained in 2022–2023 from HIV-infected treatment-naive residents of Altai Krai

Вопросы вирусологии
Introduction. Altai Krai is a region with an unfavorable situation of HIV-1 and HCV infection, as well as HIV-1 and HCV coinfection. Due to this, it is necessary to study the HCV genetic variants and their drug resistance (DR) to direct-acting antivirals
Ilya A. Lapovok, Arina V. Syrkina, Alina A. Kirichenko, Anastasia V. Shlykova, Natalya V. Lukyanenko, Tatyana V. Safyanova, Arina E. Safronova, Valery V. Shevchenko, Dmitry E. Kireev   +8 more
doaj   +1 more source

Cervicovaginal HIV-1 shedding in women taking antiretroviral therapy in Burkina Faso: a longitudinal study. [PDF]

, 2013
BACKGROUND: Antiretroviral therapy (ART) reduces transmission of HIV-1. However, genital HIV-1 can be detected in patients on ART. We analyzed factors associated with genital HIV-1 shedding among high-risk women on ART in Burkina Faso.
Kania, Dramane, Segondy, Michel, Mabey, David, Meda, Nicolas, Weiss, Helen A, Vickerman, Peter, van de Perre, Philippe, Nagot, Nicolas, Low, Andrea, Mayaud, Philippe, ?, ?, Low, Andrea J, Pillay, Deenan, Konate, Issouf, Yerelon Study Group, Weiss, Helen, Pillay, Deenan,   +16 more
core   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, EarlyView.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

Prevalence of HIV Transmitted Drug Resistance in Nanjing from 2018 to 2021

Infection and Drug Resistance, 2023
Yifan Su,1 Mingxue Qi,1 Mingli Zhong,2 Nawei Yu,1 Chen Chen,1 Zi Ye,1 Cong Cheng,1 Zhiliang Hu,1 Hongying Zhang,3 Hongxia Wei1 1Department of Infectious Disease, The Second Hospital of Nanjing Affiliated to Nanjing University of Chinese Medicine, Nanjing,
Su Y, Qi M, Zhong M, Yu N, Chen C, Ye Z, Cheng C, Hu Z, Zhang H, Wei H   +9 more
doaj  

MDR1 genetic polymorphism does not modify cell permissiveness to HIV-1 or disease progression before treatment [PDF]

, 2004
Nonphysiological overexpression of the ABC transporter Pglycoprotein (P-gp), which is encoded by MDR1, has been associated with reduced susceptibility to human immunodeficiency virus (HIV) type 1 infection in vitro.
Telenti, A, Suarez, C, Egger, Matthias, Bleiber, G, May, MT, Martinez, R, Egger, M., Telenti, Amalio, Marzolini, Catia, Martinez, Raquel, Telenti, A., Marzolini, C., Swiss HIV Cohort Study,, Marzolini, C, Bleiber, Gabriela, Suarez, C., May, Margaret, Bleiber, G., May, M., Martinez, R., Suarez, Carlos, Egger, M   +21 more
core   +2 more sources

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source