Results 191 to 200 of about 707,804 (298)

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

British Journal of Clinical Pharmacology, EarlyView.
Aims To determine breastmilk concentrations of doravirine via PBPK modelling in combination with a clinical lactation study. As women living with HIV are not able to cease antiretroviral therapy during lactation, it is necessary to establish drug transfer into breastmilk to determine exposure of the infant to antiretroviral drugs and potential risk of ...
Lena van der Wekken‐Pas, David Burger, Rick Greupink, Angela Colbers   +3 more
wiley   +1 more source

Changes in HIV-1 Reservoir Dynamics After Mpox Infection. [PDF]

J Med Virol
Casado-Fernández G, de la Calle-Jiménez O, Armenteros I, Lemus Aguilar L, Fuertes D, Cantón J, Mateos E, Cabello N, Rodríguez Añover J, Negredo A, Cervero M, Sánchez Seco MP, Torres M, Estrada V, Coiras M.   +14 more
europepmc   +1 more source

Solution structure of an RNA derived from the joint region of the TAR and PolyA stems of HIV-1 genomic RNA

Obayashi, C. M., Shinohara, Y., Masuda, T., Kawai, G.   +3 more
openalex   +1 more source

Evolution of a Species-Specific Determinant within Human CRM1 that Regulates the Post-transcriptional Phases of HIV-1 Replication

, 2011
Nathan M. Sherer, Chad M. Swanson, Stéphane Hué, Roland G. Roberts, Julien R. C. Bergeron, Michael H. Malim   +5 more
openalex   +2 more sources

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Safety of Bacillus Calmette-Guérin Vaccination and Impact on HIV-1 Latent Reservoir Size in People With Treated HIV-1 Infection. [PDF]

Open Forum Infect Dis
West E, Chaudron SE, Russenberger D, Grube C, Metzner KJ, Neumann K, Tschumi J, Kälin M, Tutumlu TK, Dollé C, Kouyos RD, Günthard HF, Braun DL, Nemeth J.   +13 more
europepmc   +1 more source

Segmental isotopic labeling of HIV-1 capsid protein assemblies for solid state NMR

, 2018
Sebanti Gupta, Robert Tycko
openalex   +2 more sources

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Resilient gut microbiome is linked to immune control in HIV-1 infection. [PDF]

Biol Direct
Silva JMM, Azevedo JLLC, Bezerra KG, Guilarde AO, Souza LCS, Guimarães RF, Leite P, Júnior HM, Gardinassi LG, Romão PRT, Fonseca SG.   +10 more
europepmc   +1 more source

Determination of the High Prevalence of Dual/Mixed- or X4-Tropism Among HIV Type 1 CRF01_AE in Hong Kong by Genotyping and Phenotyping Methods

, 2013
Sabrina Wai-Chi To, Jonathan Hon-Kwan Chen, Ka-Hing Wong, Kenny Chi-Wai Chan, Zhiwei Chen, Wing-Cheong Yam   +5 more
openalex   +2 more sources