Results 211 to 220 of about 31,026,669 (309)

A British Pharmacological Society Position Statement on Medications in Pregnancy and Lactation

British Journal of Clinical Pharmacology, EarlyView.
Agnesa Mustafa, Cleodie C. Swire, Reya V. Shah, Bernadette Jenner, Rory H. McLean, Muhammad Shamsher Ahmed, Adrie Bekker, Julia Zöllner, Rachel K. Scott, Robert R. Bies, Sara K. Quinney, Dagan O. Lonsdale, Emma Forton Magavern, Catriona Waitt, Anita Banerjee   +14 more
wiley   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise, Lena‐Marie Eberle, Holger Laux, Kerstin Otte   +3 more
wiley   +1 more source

Social Perceptions of Protection against HIV Infection among Female Street Prostitutes.

Iranian Journal of Public Health, 2014
Saeedeh Moayedi-Nia, Mohsen Naserirad, Banafshe Moradmand Badie, Asiye Ghorbani, Minoo Mohraz   +4 more
doaj  

HIV-1 Drug Resistance Mutations in Children: A Systematic Review of Global Genotypic Evidence (2014-2026). [PDF]

Pathogens
Jouf G, Alami AB, Maazaz N, Benchekroun S, Elharti E, Belbacha I, Ihazmad H, Jaoudi RE, Benhida R, Rchiad Z, Oumzil H.   +10 more
europepmc   +1 more source

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt, Richard Strasser, Christopher P. Garnham, Rima Menassa   +3 more
wiley   +1 more source

Guideline of the German Society of Neurology (DGN): "diagnosis and therapy of HIV-1-associated neurological disorders". [PDF]

Neurol Res Pract
Hahn K, Arendt G, Eggers C, Granziera C, Maschke M.   +4 more
europepmc   +1 more source

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter, Gyorgy Ovari, Anurag Kulkarni, Thomas Williams‐Fegredo, Carol Knevelman, Kyriacos Mitrophanous, Lee Davies, Farzad Foroutan, Matthew Townsend, Stephen Goldrick, Daniel G. Bracewell   +10 more
wiley   +1 more source

Genomic landscape of HIV-1 proviruses in ART-treated immunological non-responders. [PDF]

Front Immunol
Tang S, Wang Y, Lu Y, Tong Z, Guo J, Cui Y, Harypursat V, Chen Y, Ouyang J, Li H, Wang T, Zhou Q, Chen Y.   +12 more
europepmc   +1 more source

GlycoMAC: A Multiscale Metabolic‐Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng, Sarah W. Harcum, Jinxiang Pei, Wei Xie   +3 more
wiley   +1 more source

NSUN2-mediated m5C modification of HIV-1 RNA enables evasion of RIG‑I‑dependent innate immunity. [PDF]

PLoS Pathog
Xu Y, Li M, Song Y, Kong W, Song J, Zhang J, Xu X, Ma H, Yu S, Chen S, Zeng C.   +10 more
europepmc   +1 more source