Results 31 to 40 of about 141,192 (322)

Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy [PDF]

, 2014
A better understanding of changes in HIV-1 population genetics with combination antiretroviral therapy (cART) is critical for designing eradication strategies.
Angeline O'Shea, AS Perelson, B Joos, B Shi, C Shiu, Carry Poethke, Catherine Rehm, D McMahon, E Martinez, Elizabeth M. Anderson, F Maldarelli, F Maldarelli, Frank Maldarelli, G Achaz, H Hatano, H Mens, HF Gunthard, IM Rouzine, JB Dinoso, JM Benito, JM Coffin, JM Coffin, JM Cornuet, JM Llibre, John M. Coffin, John W. Mellors, Jonathan Spindler, JR Bailey, JW Cohen Stuart, K Tamura, L Ruiz, M Kearney, M Kearney, MA Martinez, MA Polis, Mary F. Kearney, MJ Buzon, N Llewellyn, Nicholas Kovacs, Q Zhang, RE Nettles, Robert F. Siliciano, RR Hudson, RT Gandhi, S Palmer, S Palmer, SA Yukl, Sloane Yu, T Elbeik, TA Wagner, TP Brennan, TW Chun, TW Chun, Wei Shao   +53 more
core   +7 more sources

HIV-1 Genetic Diversity, Volume II

, 2022
HIV-1 acquires mutations over time and the virus can also recombine when undergoing replication. Recombination between different HIV-1 subtypes can produce mosaic viral strains which, when causing epidemic spread, are called circulating recombining forms (CRFs).
Tee, Kok Keng, Thomson, Michael M, Hemelaar, Joris   +2 more
openaire   +3 more sources

HIV Types, Groups, Subtypes and Recombinant Forms: Errors in Replication, Selection Pressure and Quasispecies [PDF]

, 2012
HIV-1 is a chimpanzee virus which was transmitted to humans by several zoonotic events resulting in infection with HIV-1 groups M P, and in parallel transmission events from sooty mangabey monkey viruses leading to infections with HIV-2 groups A H.
Alvarez M, Batmanian J, Bocharov G, Brennan CA, Burgard M, Buzon MJ, Dahl V, Dai L, Domingo E, Duarte EA, Etienne L, Fang G, Fultz PN, Gunthard HF, Henriet S, Iordanskiy S, Josef Eberle, Julg B, Kijak GH, Korber B, Law M, Lemey P, Lorenzo-Redondo R, Lutz G. Gürtler, Motomura K, Neel C, Onafuwa-Nuga A, Pathak VK, Pathak VK, Rachinger A, Sauter D, Shimizu N, Simon-Loriere E, Smith DM, Sterjovski J, Swenson LC, Tienen C, Troyer JL, Van der Kuyl AC, Van der Vlist M, Zhu T   +40 more
core   +1 more source

Increasing HIV‐1 Genetic Diversity in Europe [PDF]

The Journal of Infectious Diseases, 2007
ferred from the epidemiological features of the incipient epidemic in western Europe, with most AIDS cases being diagnosed among homosexual men, who frequently referred to traveling to the United States in previous years [1, 2], and from the initial association in this population between HIV-1 seropositivity and recent visits to the United States [3 ...
Michael M. Thomson, Rafael Nájera
openaire   +1 more source

Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection.

PLoS Pathogens, 2018
In the majority of cases, human immunodeficiency virus type 1 (HIV-1) infection is transmitted through sexual intercourse. A single founder virus in the blood of the newly infected donor emerges from a genetic bottleneck, while in rarer instances ...
Katja Klein, Gabrielle Nickel, Immaculate Nankya, Fred Kyeyune, Korey Demers, Emmanuel Ndashimye, Cynthia Kwok, Pai-Lien Chen, Sandra Rwambuya, Art Poon, Marshall Munjoma, Tsungai Chipato, Josaphat Byamugisha, Peter Mugyenyi, Robert A Salata, Charles S Morrison, Eric J Arts   +16 more
doaj   +1 more source

HIV-1 infected monozygotic twins: a tale of two outcomes [PDF]

, 2011
Background Replicate experiments are often difficult to find in evolutionary biology, as this field is inherently an historical science. However, viruses, bacteria and phages provide opportunities to study evolution in both natural and experimental ...
Loubna Tazi, Hiromi Imamichi, Steven Hirschfeld, Julia A Metcalf, Susan Orsega, Marcos Pérez-Losada, David Posada, H Clifford Lane, Keith A Crandall   +8 more
core   +2 more sources

Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule.

PLoS Pathogens, 2013
Genetic recombination contributes to the diversity of human immunodeficiency virus (HIV-1). Productive HIV-1 recombination is, however, dependent on both the number of HIV-1 genomes per infected cell and the genetic relationship between these viral ...
Lina Josefsson, Sarah Palmer, Nuno R Faria, Philippe Lemey, Joseph Casazza, David Ambrozak, Mary Kearney, Wei Shao, Shyamasundaran Kottilil, Michael Sneller, John Mellors, John M Coffin, Frank Maldarelli   +12 more
doaj   +1 more source

Evolutionary Genetics of Mycobacterium Tuberculosis and HIV-1: “The Tortoise and the Hare”

Microorganisms, 2021
The already enormous burden caused by Mycobacterium tuberculosis and Human Immunodeficiency Virus type 1 (HIV-1) alone is aggravated by co-infection.
Ana Santos-Pereira, Carlos Magalhães, Pedro M. M. Araújo, Nuno S. Osório   +3 more
doaj   +1 more source

Global and regional genetic diversity of HIV-1 in 2010–21: systematic review and analysis of prevalence

Lancet Microbe, The
Malavika Nair, Lucy Gettins, Matthew Fuller, Shona Kirtley, Joris Hemelaar   +4 more
openalex   +3 more sources

Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures. [PDF]

, 2016
BACKGROUND: HIV-1 entry is a receptor-mediated process directed by the interaction of the viral envelope with the host cell CD4 molecule and one of two co-receptors, CCR5 or CXCR4.
Aiamkitsumrit, Benjamas, Antell, Gregory C, Dampier, Will, Hershberg, Uri, Jacobson, Jeffrey M, Kercher, Katherine, Krebs, Fred C, Nonnemacher, Michael R, Passic, Shendra, Pirrone, Vanessa, Schwartz, Gregory, Wigdahl, Brian, Williams, Jean W, Zhong, Wen   +13 more
core   +2 more sources