Results 41 to 50 of about 141,192 (322)

Molecular-genetic analysis of Mycobacterium tuberculosis strains spread in different patient groups in St.Petersburg (Russia) [PDF]

, 2011
Molecular epidemiological features of M.tuberculosis strains spread among different patient groups in Russia is not studied well. The aim of our study was to compare genotypes of M.tuberculosis strains circulating among TB patients from different groups:
Andrei Kozlov, Ekaterina Chernyaeva, Natalia Matveeva, Natalia Pestova, Pavel Dobrynin, Vladimir Zhemkov   +5 more
core   +3 more sources

Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques. [PDF]

, 2016
Understanding the genetic, antigenic and structural changes that occur during HIV-1 infection in response to pre-existing immunity will facilitate current efforts to develop an HIV-1 vaccine.
Bogers, WM, Fitzmaurice, TJ, Frost, SD, Heeney, JL, Hughes, J, Lai, RP, Landskron, L, McKinley, Trevelyan J., Mooj, P, Varela, M, Verschoor, E, Willett, BJ   +11 more
core   +1 more source

Human T-Cell Leukemia Virus Type 1-Related Diseases May Constitute a Threat to the Elimination of Human Immunodeficiency Virus, by 2030, in Gabon, Central Africa

Viruses, 2022
The Joint United Nations Program on HIV/AIDS (UNAIDS) has adopted the Sustainable Development Goals (SDGs) to end the HIV/AIDS epidemic by 2030. Several factors related to the non-suppression of HIV, including interruptions of antiretroviral therapy (ART)
Eldridge Fedricksen Oloumbou, Jéordy Dimitri Engone-Ondo, Issakou Mamimandjiami Idam, Pamela Moussavou-Boudzanga, Ivan Mfouo-Tynga, Augustin Mouinga-Ondeme   +5 more
doaj   +1 more source

The origin of genetic diversity in HIV-1

Virus Research, 2012
One of the hallmarks of HIV infection is the rapid development of a genetically complex population (quasispecies) from an initially limited number of infectious particles. Genetic diversity remains one of the major obstacles to eradication of HIV. The viral quasispecies can respond rapidly to selective pressures, such as that imposed by the immune ...
Redmond P, Smyth, Miles P, Davenport, Johnson, Mak   +2 more
openaire   +2 more sources

Cross-reactivity of anti-HIV-1 T cell immune responses among the major HIV-1 clades in HIV-1-positive individuals from 4 continents [PDF]

, 2005
Background. the genetic diversity of human immunodeficiency virus type 1 (HIV-1) raises the question of whether vaccines that include a component to elicit antiviral T cell immunity based on a single viral genetic clade could provide cellular immune ...
Chisi, J., Collins, K. B., Condra, J. H., Coplan, P. M., Dubey, S. A., Emini, E. A., Freed, D. C., Fu, T. M., Gray, G., Guess, H. A., Gupta, S. B., Kallas, Esper Georges, Kublin, J., Mast, C. T., Mbewe, B., Mcintyre, J., Mehrotra, D. V., Nikas, A., Pendame, R., Pitisuttithum, P., Puthavathana, P., Schechter, M., Shiver, J. W., Straus, W. L., Thaler, S. J., Vardas, E.   +25 more
core   +1 more source

Characterization update of HIV-1 M subtypes diversity and proposal for subtypes A and D sub-subtypes reclassification

Retrovirology, 2018
Background The large and constantly evolving HIV-1 pandemic has led to an increasingly complex diversity. Because of some taxonomic difficulties among the most diverse HIV-1 subtypes, and taking advantage of the large amount of sequence data generated in
Nathalie Désiré, Lorenzo Cerutti, Quentin Le Hingrat, Marine Perrier, Stefan Emler, Vincent Calvez, Diane Descamps, Anne-Geneviève Marcelin, Stéphane Hué, Benoit Visseaux   +9 more
doaj   +1 more source

Genetic diversity in the env V1-V2 region of proviral quasispecies from long-term controller MHC-typed cynomolgus macaques infected with SHIVSF162P4cy [PDF]

, 2018
Intra-host evolution of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) has been shown by viral RNA analysis in subjects who naturally suppress plasma viremia to low levels, known as controllers.
Borsetti, Alessandra, Capone, Alessia, Cella, Eleonora, Ciccozzi, Massimo, Ensoli, Barbara, Farcomeni, Stefania, Ferrantelli, Flavia, Lo Presti, Alessandra, Maggiorella, Maria T, Mee, Edward T, Rose, Nicola J, Sernicola, Leonardo   +11 more
core   +1 more source

Population Structure and Implications on the Genetic Architecture of HIV-1 Phenotypes Within Southern Africa

Frontiers in Genetics, 2019
The interesting history of Southern Africa has put the region in the spotlight for population medical genetics. Major events including the Bantu expansion and European colonialism have imprinted unique genetic signatures within autochthonous populations ...
Prisca K. Thami, Prisca K. Thami, Emile R. Chimusa   +2 more
doaj   +1 more source

Transmitted HIV Drug Resistance in Bulgaria Occurs in Clusters of Individuals from Different Transmission Groups and Various Subtypes (2012–2020)

Viruses, 2023
Transmitted HIV drug resistance in Bulgaria was first reported in 2015 using data from 1988–2011. We determined the prevalence of surveillance drug resistance mutations (SDRMs) and HIV-1 genetic diversity in Bulgaria during 2012–2020 using polymerase ...
Ivailo Alexiev, Anupama Shankar, Yi Pan, Lyubomira Grigorova, Alexandra Partsuneva, Reneta Dimitrova, Anna Gancheva, Asya Kostadinova, Ivaylo Elenkov, Nina Yancheva, Rusina Grozdeva, Dimitar Strashimirov, Mariana Stoycheva, Ivan Baltadzhiev, Tsetsa Doichinova, Lilia Pekova, Minas Kosmidis, Radoslava Emilova, Maria Nikolova, William M. Switzer   +19 more
doaj   +1 more source

Genome-Wide Association Study of Human Immunodeficiency Virus (HIV)-1 Coreceptor Usage in Treatment-Naive Patients from An AIDS Clinical Trials Group Study [PDF]

, 2014
OBJECTIVES: We conducted a genome-wide association study to explore whether common host genetic variants (>5% frequency) were associated with presence of virus able to use CXCR4 for entry.
de, PIW, Giguel, F, Gulick, RM, Hanhauser, E, Henrich, Timothy, Henrich, TJ, Kuritzkes, DR, Lin, NH, McLaren, PJ, Rao, SSP, Ribaudo, H   +10 more
core   +2 more sources