Results 191 to 200 of about 2,695,708 (355)

Labor Market Outcomes of People with HIV Pre- and Post-Diagnosis in the Netherlands. [PDF]

Nat Commun
Tuiu A, Zwiers E, Janssens W, Jongen V, van Sighem A, Wit F, Pradhan M, van der Valk M.   +7 more
europepmc   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Psychological Well-Being Challenges and Associated Coping Mechanisms of HIV/AIDS Counselors in the Volta Region of Ghana: A Descriptive Phenomenological Study. [PDF]

J Int Assoc Provid AIDS Care
Charles-Unadike VO, Dwomoh F, Ampomah MA, Manu E.   +3 more
europepmc   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

HIV expression persists in the cerebrospinal fluid of HIV-associated neurocognitive disorders despite effective ART. [PDF]

Emerg Microbes Infect
Prates GS, Li X, Folgosi V, Shabangu CS, Souza GG, Apoliano C, Gascon MR, Monteiro MA, Gualqui C, Santos Eichler R, Gomes H, Katuwal N, Gilbert C, Tang Y, Casseb J, Jiang G.   +15 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

The sustainability of public health programs following donor transition: A comparative case study of HIV services and maternal and newborn care in Uganda. [PDF]

PLoS One
Zakumumpa H, Ssegujja E, Kyomuhendo M, Maritim B, Musila T, Ssengooba F.   +5 more
europepmc   +1 more source

Assessing transporter‐mediated rifampin–linezolid interaction using physiologically‐based pharmacokinetic modelling

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The study aims to develop a physiologically‐based pharmacokinetic (PBPK) model to quantitatively evaluate the role of ATP‐binding cassette sub‐family B member 1 (ABCB1) and ATP‐binding cassette super‐family G member 2 (ABCG2) in the drug–drug interaction (DDI) between rifampin and linezolid and to predict the impact of high‐dose rifampin ...
Hoang Dat Nguyen, Vinh Hoa Pham, Richard M. Hoglund, Joel Tarning, Junjie Ding   +4 more
wiley   +1 more source

Piloting the feasibility of a population-based joint TB-HIV survey in KwaZulu-Natal Province, South Africa, 2019. [PDF]

PLOS Glob Public Health
Murangandi P, Oladimeji O, Zungu N, Makola L, Marinda E, Simbayi L, Zuma K, Ramlagan S, Jooste S, Maseko G, Naidoo I, Nwosu C, McCracken S, Moyo S, Hladik W.   +14 more
europepmc   +1 more source